Curation

In 1971 the Protein Data Bank - PDB [146] (see Section 5.8 for a complete story and description) - was established at Brookhaven National Laboratories - BNL -as an archive for biological macromolccular cr7stal structures. This database moved in 1998 to the Research Collaboratory for Structural Bioinformatics -RCSB. A key component in the creation of such a public archive of information was the development of a method for effreient and uniform capture and curation of the data [147], The result of the effort was the PDB file format [53], which evolved over time through several different and non-uniform versions. Nevertheless, the PDB file format has become the standard representation for exchanging inacromolecular information derived from X-ray diffraction and NMR studies, primarily for proteins and nucleic acids. In 1998 the database was moved to the Research Collaboratory for Structural Bioinformatics - RCSB. 

K. Bachmaim, ed.. Conservation Concerns A Guide for Collections and Curators, Smithsonian Institution Press, Washington, D.C., 1992. 

This handbook provides y oci with quick. ind, ii curate solutions to your everyday pipeline problems. With 100 more pages than the Setond Edilion, n saves you valuable time and elforl with useful tips on conversion tactors, construction and design, gas engineering, oil products, corrosion, economics and much more. 

Sulfur dioxide DMS (single-backed) T etrachloromer-curate (II) 0.01 ppm (8-hr exposure)... 

The above technique has the practical inconvenience of requiring as many different sets of Tchebyschev coefficients as the unit cell non equivalent sublattices. Furthermore, for non cubic systems, these coefficients depend on the lattice distortion ratios. Namely, for tetragonal lattices different sets of coefficients are required for each value of c/a. This situation has made difficult the implementation of KKR and KKR-CPA calculations for complex lattice structures as, for example, curates. 

In the biosciences, a database is a curated repository of raw data containing annotations, further analysis, and links to other databases. Examples of databases are the SWISSPROT database for annotated protein sequences or the FlyBase database of genetic and molecular data for Drosophila melanogaster. 

Swiss-Prot ia a curated databank of information on protein sequence, structure and function. It can be found under http //www.ebi.ac.uk/swissprot/. 

A recent review has described the numerous commercial concerns that are involved in systems biology by providing either software or services [24]. Large, curated interaction databases combined with powerful analytical... 

Although not a very recent development, measurement of U-series isotopes by gamma spectrometry is worth a mention here because of its increasing application to the dating of bones. About 50 mg, or less, of bone is required for a TIMS U-series measurement, although a bone section is required if profiles are to be measured for the application of the D-A model. Understandably, museum curators are reluctant to allow the most valuable specimens to be cut or drilled, so the non-destructive measurement of a U-series date is extremely advantageous. 

Screening brings back a rich variety of information, not just what the curator put in the database. Suddenly a chemist can read everything about a molecule ever printed, not just what someone decided to associate it with. Distant associations -A related to B and B related to C might mean A related to C- will become apparent. 

The reluctance of museum curators and collectors to allow permanent damage to antiquities was, until not long ago, the main reason for the small amount of analytical work done on ancient coins. This was understandable since performing chemical analysis required removing a sample from the coin or damaging its surface, which meant either the destruction or defacement of, at least, a portion of a coin. More recently, however, a number of nondestructive methods of analysis such as neutron activation, X-ray fluorescence, and some techniques of surface analysis have been successfully applied to obtain information about ancient coins and the people and societies involved in their production (Carter 1993 Barrandon et al. 1977). 

Mercuric 2//-hexafluoroisobutyrate, [(CF3)2CHC02]2Hg, when heated in refluxing pyridine (30) or to 40-50° C in dmf (31) gave bis(l//-hexafluoroisopropyl)mercury, [(CF3)2CH]2Hg. Competition between mer-curation and decarboxylation was studied by repeating the reaction in dmf in the presence of mercuric acetate (31). The main path was found to be mercuration at the a carbon of the hexafluoroisobutyrate group followed by decarboxylation. The low yield of bis(l//-hexafluoroisopropyl)mercury showed that carbon dioxide elimination is slower than mercuration under these conditions. 

These reductions are further utilized to alkylate organotin compounds. The stannylmer-curate intermediates formed during electrolysis are reactive towards alkyl halides, mostly iodide and bromide. The reactivity pattern follows the order R = Me, Et, Bu, > Ph. Alkylations are therefore observed when electrolysis is carried out in the presence of R X ... 

Interesting ice samples from Antarctica and Greenland have been and are being recovered. We studied samples of the Byrd core, which is a 12-cm-diameter core that extended to bedrock at 2100-m depth [1]. This core is presently kept at the Central Ice Core Storage Facility at S.U.N.Y. Buffalo (C. C. Langway, Jr., Curator). Its age-depth relationship has been calculated on the basis of rheological models [3,4,5], and comparisons of the 6180 variations of the core with those in the Camp Century (Greenland) core. The age calculated for the bottom ice is between 50 x 103 and 100 x 103 years. 

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