Interaction databases

Once the model parameters have been estimated, analysts should perform a sensitivity analysis to establish the uniqueness of the parameters and the model. Figure 30-9 presents a procedure for performing this sensitivity analysis. If the model will ultimately be used for exploration of other operating conditions, analysts should use the results of the sensitivity analysis to estabhsh the error in extrapolation that will result from database/model interactions, database uncertainties, plant fluctuations, and alternative models. These sensitivity analyses and subsequent extrapolations will assist analysts in determining whether the results of the unit test will lead to results suitable for the intended purpose. 

Prospector web Prospector Web is an interactive database used to find and compare plastic materials. You can specify your application requirements to search a catalog of nearly all North American plastics and increasing amounts of plastics data from European and Pacific Rim material suppliers. Materials can be searched by any of 200+ properties, reviewed, sorted, and compared to determine the material best fitted to your needs. Test data is available in both English or Metric units and ASTM or ISO format. Both Prospector Web and its sister product Prospector Desktop come with IDES s exclusive Plastics Materials Hotline to help with questions that may arise. 

A recent review has described the numerous commercial concerns that are involved in systems biology by providing either software or services [24]. Large, curated interaction databases combined with powerful analytical... 

Interactions Database of Interacting http //dip.doe-mbi.ucla.edu/ Interactions between... 

Licata L, Briganti L, Peluso D et al (2011) MINT, the molecular interaction database 2012 update. Nucleic Acids Res 40 D857-D861... 

Washington, U. O. (2003) Dmg Interaction Database http //depts.washington.edu/ didbase/index. shtml. 

Chatr-aryamontri, A., Ceol, A., Palazzi, L.M., Nardelli, G., Schneider, M.V., Castagnoli, L. and Cesareni, G. (2007) MINT The Molecular INTeraction Database. Nucl Acids Res, 35, D572-D574. 

Pagel, P., Kovac, S., Oesterheld, M., Brauner, B., Dunger-Kaltenbach, L, Frishman, G., Montrone, C., Mark, P., Stumpflen, V., Mewes, H.-W., et al, (2005) The MIPS Mammalian Protein-Protein Interaction Database. Bioinformatics, 21, 832-834. 

Genes2Networks Connecting Lists of Gene Symbols Using Mammalian Protein Interactions Databases. BMC Bioinform, 8, 372. 

NMDA Receptors, Neural Pathways, and Protein Interaction Databases... 

These values were obtained from the University of Washington s Metabolism and Transport Drug Interaction Database http //www.druginteractioninfo.org rfOgilvie et al. (217). 

Metabolism and Transport Drug Interaction Database A Web-Based Research and Analysis Tool... 

The Metabolic and Transport Dmg Interaction Database (DIDB) (http //www. dmginteractioninfo.org), developed by the Dmg Interaction Prediction group at the University of Washington, includes one of the largest set of comprehensive... 

Figure 1 Drug query labeled multiple objects used to find in vivo inhibitors of CYP2B6. Display from the Metabolism and Transport Dmg Interaction Database (http // www.druginteractioninfo.org, accessed October 2006).

Carlson SP, Ragueneau-Majlessi I, Levy RH. Development of a metabolic drug interaction database at the University of Washington. In Rodrigues AD, ed. Drugs and the Pharmaceutical Sciences, vol. 116. New York Marcel Dekker Inc, 2002 549-563. 

Hoffman MM, Kharpov MA, Cox JC, Yao J, Tong J, Ellington AD (2004). AANT The Amino Acid—Nucleotide Interaction Database. Nucleic Acid Res 32 D174—D181. 

Sherman, D., Apweiler, R. (2004b). IntAct an open source molecular interaction database. Nucleic Acids Res. 32, D452-D455. 

Mark, P., Stumpelen, V., Mewes, H. W., etal. (2005). The MIPS mammalian protein-protein interaction database. Bioinformatics 21, 832-834. 

Zanzoni, A., Montecchi-Paiazzi, L., Quondam, M., Ausiello, G., Helmer-Citterich, M. Cesareni, G. (2002). MINT a Molecular INTeraction database. FEBS Lett. 513,135-140. 

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