Controlled release applications strategies

In the forementioned laboratories, we started with a new strategy based on phase separation in order to prepare natural particles. Simple or complex coacervation methods involving proteins or protein and polysaccharide mixtures3 were used to create new matrices dedicated to controlled release applications. The colloidal carriers produced were in the micrometre or nanometre size range depending on the substrates or the methods used. Wheat proteins, gliadins, were implicated in simple coacervation to produce nanospheres. Controlled release experiments with model compounds were conducted in order to evaluate... 

The most intensive effort to use pheromones in insect management has been in Australia, where an attract-and-kill strategy has been developed for protecting stone fruit crops. Historically, the Oriental fruit moth, Grapholita molesta Busck, was the major stone fruit pest, and heavy insecticide applications kept both this moth and, coincidentally, the Carpophilus beetles at acceptable levels. However, the widespread adoption of pheromone-based mating disruption for G. molesta control released the Carpophilus beetles from insecticide pressure, and these beetles, Ca. davidsoni in particular, became the dominant stone fruit pests (James et al., 1994). Late applications of broad-spectrum insecticides often... 

In the context of controlled release, the layer-by-layer fabrication procedure offers potential advantages over conventional protein and nucleic acid encapsulation strategies, including the ability to control the order and location of multiple polymer layers with nanometer scale precision, and the ability to define the concentrations of incorporated materials simply by varying the number of polymer layers incorporated [190-192]. Although numerous reports describe the application of these materials to the sustained release of permeable small molecules [193-197], there are few examples of these assemblies designed to release macromolecular components. Several groups have performed... 

G. Ma, Microencapsulation of protein drugs for drug delivery Strategy, preparation, and applications. Journal of Controlled Release, 193 (0) 324-340, 2014. 

In controlled release systems, pectin can be applied as an additive, with great potential for nasal, oral [52], and ocular [88] drugs. The field of biomaterials has a very wide range of applications of nano-and microparticles of pectin. New strategies for particle are needed for better-quality production. Bioengineering, chemistry, material science and health sciences can be combined to achieve more complete and better results [93]. 

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