Contraction local

An initial hint that Ca2+ stores are present and functional in smooth muscle cells came from earlier experiments revealing that agonist-induced contractions could be observed in the absence of extracellular Ca2+. It is now known that smooth muscle Ca2+ stores express two types of Ca2+ release channels, the ryanodine receptor (RyR) and the inositol-1,4,5-trisphosphate (L1SP3) receptor (L1SP3R) (Somlyo Somlyo 1994). Recent studies have shown that Ca2+ release from intracellular Ca2+ stores plays various important roles in the regulation of smooth muscle contraction. Local and transient releases of Ca2+ from RyR near the surface membrane, which are called Ca2+ sparks, activate Ca2+-sensitive K+... 

Similar changes take place in the development of skeletal muscle, but the ability to contract appears somewhat later. In the chick embryo, the first contractions, localized in the muscles of the head and neck, appear at 3 -4 days of development, but distal leg muscles do not begin to contract until 7i days, and distinct motor end plates do not appear until day 13 or 14 (Hamburger, 1968). 

The caudal hand monitors for muscle contraction localized to the fibers being treated. 

Entities involved in long-term contracts with electric utihties, such as fuel supphers and NUGs selling power to utihties, also have concerns that some utihties or industrial customers will not be able to honor their contracts under the new, more competitive system. Einahy, some utihties are concerned that they wih not be adequately reimbursed for opening up their transmission systems to competitors. The potential competitors in turn are concerned that utihties whl not provide unbiased access to their transmission systems if the utihties themselves are also in business of marketing power. There has also been some debate regarding which transmission facihties are eligible for open access. This is because some facihties are considered local distribution systems by utihties, which feel they should not be opened to competitors. 

Cogeneration systems will not match the varying power and heat demands at all times for most applications. Thus, an industrial cogeneration systems output frequently must be supplemented by the separate on-site generation of heat or the purchase of utility-supplied elec tric power. If the on-site electric power demand is relatively low, an alternative option is to match the cogeneration system to the heat load and contract for the sale of excess electricity to the local utihty grid. 

Medical surveillance programs range from support contracts with local hospitals or physicians to full-scale on-site occupational health organizations that include physicians, nurses, and technicians who are employed by prime contractors. The option selected depends on the size of the project, the nature of the hazards involved, the capabilities of local facilities, and the resources available. 

When exposure is repeated, the allergen binds between two adjacent IgE molecules. This causes release of inflammatory mediators (histamine, leukotrienes, chemotactic factors). These act locally and cause smooth muscle contraction, increased vascular permeability, mucous gland secretion, and infiltration of inflammatory cells (neutrophils and eosinophils). However, histamine can also be released by non-IgE-mediated mechanisms (e.g., due to exposure to certain fungi). 463... 

The third transition procedure defines the rules under which competitive suppliers of electricity can compete for end users. There are two polar models that are often debated for power market organization the direct access (or bilateral contracts) regime, and the Poolco regime. Under direct access, consumers enter into direct contracts with competitive suppliers of electricity, and competitive providers of electricity enter into contracts with, and pay an access fee to, the local (regulated) distribution company for the use of local power lines. 

The Environmental Protection Agency (EPA) and other federal, state and local authorities govern security of supply in relation to quantity for surface and groundwater by the granting of an abstraction license. The license limits the total daily quantity and the rate at which the waters may be abstracted, taking account of the natural resource and the needs of other abstractors. Metered water supply is subject to contract with the water companies, who may impose quantity and draw-off rate limitations. The limitations imposed by the license or contract may influence plant location. 

Electrodeposits are usually in a state of internal stress. Two types of stress are recognised. First order, or macro-stress, is manifest when the deposit as a whole would, when released from the substrate, either contract (tensile stress) or expand (compressive stress) (Fig. 12.12). Second order or microstress, occurs when individual grains or localities in the metal are stressed, but the signs and directions of the micro-stresses cancel on the larger scale. The effects of first order stress are easily observed by a variety of techniques. 

Envisioning space-time as a four-dimensional CA lattice, wherein sites take on one of a finite number of values and interact via a local dynamics, Minsky explored various elementary properties of this universe particle (or packet ) size and speed, time contraction, symmetry, and how the notion of field might be made palatable within such a framework. 

Kirby (K3) has found an interesting hypothesis that works in the net quality region. It is a contraction of Barnett s local-conditions hypothesis [Eq. (10)] and is therefore not strictly applicable at low qualities where slight... 

First, the function e(t) computed from e(x) (Fig. 33), is divided into a number of time intervals which are sufficiently short to justify the approximation of a constant average strain-rate within each period. Only the region of space where the strain rate is significantly different from zero, i.e. from — 4r 5 x +r0 in the case of abrupt contraction flow (Fig. 33), will contribute to the degradation and needs to be considered in the calculations. The system of Eq. (87) is then solved locally using the previously mentioned matrix technique [153]. 

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