Conjugation influence acids

Ferraro TN, Hare (1985) Free and conjugated amino acids in human CSF influence of age and sex. Brain Res 338 53-60... 

Donovan, D.C., Schingoethe, D.J., Baer, R.J., Ryali, J., Hippen, A.R., Franklin, S.T. 2000. Influence of dietary fish oil on conjugated linoleic acid and other fatty acids in milk fat from lactating dairy cows../ Dairy Sci. 83, 2620-2628. 

Griinari, J.M., Bauman, D.E., Chilliard, Y., Perajoki, P., Nurmela, K.V.V. 2000a. Dietary influences on conjugated linoleic acids (CLA) in bovine milk fat. 3rd Meeting European Section of AOCS, Helsinki, pp. 87. 

Kritchevsky, D., Tepper, S.A., Wright, S., Tso, P., Czarnecki, S.K. 2000. Influence of conjugated linoleic acid (CLA) on establishment and progression of atherosclerosis in rabbits.. / Am. Coll. Nutr. 19, 472S t77S. 

Lawless, F., Stanton, C., L Escop, P., Devery, R., Dillon, P., Murphy, J.J. 1999. Influence of breed on bovine milk cis-9, trans-l 1-conjugated linoleic acid content. Livest. Prod. Sci. 62, 43-49. 

Thompson, H.J., Zhu, Z.J., Banni, S., Darcy, K., Loftus, T., Ip, C. 1997. Morphological and biochemical status of the mammary gland as influenced by conjugated linoleic acid Implication for a reduction in mammary cancer risk. Cancer Res. 57, 5067-5072. 

Opposing effects of certain individual fatty acids could have influenced the lack of a relationship between dietary fat and fat type with the risk of breast cancer. Well-conducted animal studies suggest that linoleic acid promotes development of mammary tumors, whereas saturated, monounsatu-rated, and trans fatty acids have little or no effect. In many cases, w-3 polyunsaturated fatty acids suppress tumor development. Conjugated linoleic acid (CLA) is the most potent anti-cancer fatty acid in that amounts of 1% or less of dietary fat can substantially inhibit the development of mammary tumors (Ip, 1997). 

Dhiman, T.R., Zaman, M.S., Kilmer, L., and Gilbert, D. 2002. Breed of dairy cows has influence on conjugated linoleic acid (CLA) content of milk. J. Dairy Sci. 85(Suppl. 1), 315.(Abstr.). 

Hayek MG, Han SN, Wu D, Watkins BA, Meydani M, Dorsey JL, et al. Dietary conjugated linoleic acid influences the immune response of young and old C57BL/6NCrlBR mice. J Nutr 1999 129 32-38. 

The microsomal 12a-hydroxylase seems to be influenced by the flux of bile acids through the liver in a similar way as cholesterol 7a-hydroxylase. Biliary drainage in rats leads to a 2-fold stimulation of 12a-hydroxylase [44] perhaps due to reduced intake of food [252]. However, it was shown later that 12a-hydroxylation of 7a-hydroxy-4-cholesten-3-one was inhibited by feeding rats different taurine-conjugated bile acids at the 1% level [110]. Ahlberg et al. showed that the microsomal 12a-hydroxylase in human liver was inhibited by about 50% after treatment for 8 weeks with chenodeoxycholic acid, 15 mg/kg body weight [HI]. The increased ratio between cholic acid and chenodeoxycholic acid observed after treatment with cholestyramine is also consistent with an inhibitory effect of reabsorbed bile acids on the 12a-hydroxylase [219]. 

Peters, J. M., Park, Y., Gonzalez, F. J., and Pariza, M. W. Influence of conjugated linoleic acid on body composition and target gene expression in peroxisome proliferator-activated receptor alpha-null mice. Biochim Biophys Acta 1533 (2001) 233-242. 

Influence of Dietary Conjugated Linoleic Acid (CLA 2.5%) on the Fatty Acid Composition of Total Lipids, Triacylglycerols, Phosphatidylcholine (PC), and Phosphatidylethanolamine (PE)... 

Turek, J J., Li, Y, Schoenlein, L.A., AUen, K.G.D., and Watkins, BA. (1998) Modulation of Macrophase Cytokine Production by Conjugated Linoleic Acids Is Influenced by the Dietary n-6 n-3 Fatty Acid Ratio, J. Nutr. Biochem. 9,258-266. 

Stanton, C., Lawless, R, Kjelhner, G., Harrington, D., Devery, R., Connolly, J.E., and Murphy, J. (1997) Dietary Influences on Bovine Milk cw-97ranj -11-Conjugated Linoleic Acid Content, J. Food Sci. 62,1083-1086. 

Banni, S., Angioni, E., Carta, G., Casu, V., Deiana, M., Dessi, M.A., Lucchi, L., Melis, M.P., Rosa, A., Vargiolu, S., and Corongiu, F.P. (1999) Influence of Dietary Conjugated Linoleic Acid on Lipid MetaboUsm in Relation to Its Anticar-cinogenic Activity, Advances in Conjugated Linoleic Acid Research, Volume 1 (Yurawecz, M.P., Mossoba, M.M., Kramer,... 

Influence of Conjugated Linoleic Acid (CLA) Isomers and CLA Mix on Experimental Atherosclerosis in Rabbits ... 

Little information exists on the influence of bile acids on electrolyte and water movements in the small intestine. Forth et al. (107) noted that deoxy-cholic acid, but not conjugated bile acids, inhibited water and electrolyte absorption systematic examination of the effect of nucleus substitution and presence and type of conjugation was not carried out. No information is available at present on the influence of bile acids on water movements in the human jejunum and ileum. 

Thyroid activity also influences bile acid conjugation. In ten hypothyroid patients, the mean ratio of glycine-conjugated/taurine-conjugated bile acids was 8.8. The mean value after treatment with desiccated thyroid or thyroxine to restore a euthyroid state was 3.4, corresponding quite closely to the mean value of 3.1 for normal subjects (8). 

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