Compounds smell

What other types of material would have a set of properties in the range of the desired properties For instance, which class of compounds smells even better than musk, and where would we find a cure of lung cancer This is symbolically written as. v = g(y). 

Determine the time and nitrogen flow rate so that breakthrough (no more retention for a given substance) of the trap does not occur. Do this by attaching a second trap in series and analyzing this trap. For aroma compounds, smell the end of the trap to detect odor-active compound leakage. Even if the vessel is heated, the trap should be kept at room temperature. 

By an improved solid-phase extraction procedure, 2-methyl-tetrahydro-furan-3-thiol 77 could be measured in wine at levels of 0.2 ng/L (01MI533, 08JC(A)9). This compound smells like strongly cooked meat, described as roasted meaty. From grape cultivars of the Vinho Verde region in Portugal 2-methyl-tetrahydrothiophen-3-one 78 was isolated (02ACA157). 

Interesting is the strong effect of monofluorophosphoric acid alkyl ester on the human organism. The vapours of the compounds smell pleasant and aromatic. However, just a few minutes after breathing there is a strong pressure against the head, connected... 

The presence of 2-methyl-furanthiol, an odoriferous compound smelling of cooked meat with a perception threshold in model solution of approximately 5 ng/1, has been reported in red Bordeaux (Bouchilloux et al., 1998a Kotseridis and Baumes,... 

Markarian J. Compounders smell success in packaging. Plastics Addit Compound [trade journal—Elsevier Ltd.) January/February 2006. 

A compound smells if it is sufficiently volatile. This applies predominantly not only to monoterpenes, but also to various sesqui- and diterpenes, as fragrances reach the appropriate receptors of the epithelium of the olfactory organ in the upper part of the nose. A molecule induces a specific sense of smell in the nose provided that its shape exactly matches a complementary cavity of the receptor, much as a key fits into a lock. Therefore, according to the stereochemical theory of odor developed by Amoore which only crudely interprets the complicated process of sensory perception, the smell of a compound correlates with the shape of its molecule. 

Almost all of the low-molecular-weight amines have objectionable (to humans) odors. Many of the compounds smell fishy and, indeed, the odor of rotting fish has been attributed to such materials. Some diamines produced by the action of bacteria on decaying organic materials enjoy names refiective of their unpleasant odors, for example, putrescine [H2N(CH2)4NH2] and cadaverine [H2N(CH2)5NH2]. 

The compounds have limited value as dye-stufTs intermediates, nitrobenzenef CeHjNOj, PhN02-Colourless, highly refractive liquid with characteristic smell m.p. b.p. 21 TC. 

At room temperature ozone is a slightly blue diamagnetie gas which condenses to a deep blue liquid. It has a characteristic smell, and is toxic. Ozone is a very endothermic compound ... 

The zinc alkyls, of which this is an example, are vile-smelling inflammable liquids. They were the first organo-metallic compounds prepared by Frankland in 1849. With water, they decompose giving an alkane ... 

Revision Problem 4 Musks are compounds which have some pleasant smell themselves, but function chiefly by retaining and enhancing the perfume of other compounds. How might celestoHde , a modem musk, (TM 398) be made ... 

Suffice to say that anything that remotely smells like sassafras oil or licorice or any of those strong rustic spices is going to have some amphetamine precursor, maybe not safrole exactly, but definitely something. There is just no other substitute in nature for the aroma these unique compounds give. 

Compounds related to benzene were obtained from similar plant extracts Eor example a pleasant smelling resin known as tolu balsam was obtained from the South American tolu tree In the 1840s it was discovered that distillation of tolu balsam gave a methyl derivative of benzene which not surprisingly came to be named... 

Essential oils (Section 26 7) Pleasant smelling oils of plants consisting of mixtures of terpenes esters alcohols and other volatile organic substances Ester (Sections 4 1 and 20 1) Compound of the type... 

Ammonia is a volatile compound as evidenced by the strong smell of even dilute solutions. This volatility presents a possible source of determinate error. Will this determinate error be negative or positive ... 

Human perception creates difficulty ia the characterization of flavor people often, if not always, perceive flavors differently due to both psychological and physiological factors. For example, certain aryl thiocarbamates, eg, phenylthiocarbamide, taste exceedingly bitter to some people and are almost tasteless to others (5). This difference is genetically determined, and the frequency of its occurrence differs from one population to another 40% of U.S. Caucasians are nontasters, whereas only 3% of the Korean population caimot perceive the strong bitter taste of the aryl thiocarbamates (6). Similar differences were found ia the sense of smell for compounds such as menthol, carvone, and ethyl butyrate (7). 

Sensory perception is both quaUtative and quantitative. The taste of sucrose and the smell of linalool are two different kinds of sensory perceptions and each of these sensations can have different intensities. Sweet, bitter, salty, fmity, floral, etc, are different flavor quaUties produced by different chemical compounds the intensity of a particular sensory quaUty is deterrnined by the amount of the stimulus present. The saltiness of a sodium chloride solution becomes more intense if more of the salt is added, but its quaUty does not change. However, if hydrochloric acid is substituted for sodium chloride, the flavor quahty is sour not salty. For this reason, quaUty is substitutive, and quantity, intensity, or magnitude is additive (13). The sensory properties of food are generally compHcated, consisting of many different flavor quaUties at different intensities. The first task of sensory analysis is to identify the component quahties and then to determine their various intensities. 

Quality Control. Reproducible production of perfumes requires careful quality control of all materials used as well as the compounding process itself. The use of analytical tools has iacreased over the years with their availability, but there can be no substitute for organoleptic evaluation. The human nose is far more sensitive than any analytical instmment for certain materials, yet it is also quite limited as a quantitative tool and is subject to fatigue. There are also weU-documented examples of specific anosmias ia iadividuals, ie, iaability to smell certain odor types, which is somewhat analogous to color-blindness. 

Cross-country gas pipelines generally must odorize the normally odorless, colorless, and tasteless gas ia urban and suburban areas, as is required of gas distribution companies. Organosulfur compounds, such as mercaptans, are usually used for this purpose, and code requires that the odor must be strong enough for someone with a normal sense of smell to detect a gas leak iato air at one-fifth the lower explosive limit of gas—air mixtures. The latter is about 5%, so the odorant concentration should be about 1%, but most companies odorize more heavily than this as a safety precaution. 

Synthesis of steroidal diazirines has led to some biologically active compounds (65JA2665). The observation that diazirines and their parent ketones are identical in smell (B-67MI50800), points to the possibility that a diazirine group may stand for a keto group vis-d-vis a receptor. 

---