Wounds composite dressings

Wittaya-Areekul S. and Prahsarn C., Development and in vitro evaluation of chitosan-poly saccharides composite wound dressings , Int J Pharm, 313,123-128,2006. 

Cummings, G.W., Cummings, R., 1999. Composite wound dressing with separable components, US patent 5,910,125. 

J.J. Eisner, D. Egozi, Y. Ullmann, I. Berdicevsky, A. Shefy-Peleg, M. Zilberman, Novel biodegradable composite wound dressings with controlled release of antibiotics Results in a guinea pig burn model. Burns, 37, 896-904, 2011. 

First composite wound dressing -Gamgee tissue. Produced as cotton or viscose fiber in a retaining sleeve. First film dressing Isinglassplaster used after skin grafting. Composed of fish swim bladder sja-ead onto layer of oiled silk. 

The objectives of this research were to determine the viability and efficacy of a composite wound dressing, mentioned above, utilizing in vitro and in vivo studies. We desired to evaluate these dressings in the presence of biological tissues in order to determine their effectiveness in epithelialization and overall wound healing. 

Because of the extraordinary supramolecular structure and exceptional product characteristics as high-molecular and high-crystalline cellulosics with a water content up to 99%, nanocelluloses require increasing attention. This review assembles the current knowledge in research, development, and application in the field of nanocelluloses through examples. The topics combine selected results on nanocelluloses from bacteria and wood as well as their use as technical membranes and composites with the first longtime study of cellulosics in the animal body for the development of medical devices such as artificial blood vessels, and the application of bacterial nanocellulose as animal wound dressings and cosmetic tissues. 

When chitosan is added to the culture medium the BC/chitosan composites formed include the properties of both components, mainly an extraordinary bactericidal and barrier effect against microorganisms. Therefore, this modified BC is well suited for wound dressings [42]. 

An alternative to the acrylamide-based composite hydrogel dressing is an acrylamide grafted to a polyurethane film to give a transparent, flexible gel with an equilibrium water content of approximately 50 /o. The hydrated gel has a low modulus of elasticity and a high water permeability that facilitates the adherence of the gel to the wound surface. The permeability... 

Modern-day diets are composed of foods from all five Continents and often reflect the elemental compositions of the soil used to grow those crops and to raise the animals, as mentioned in Chapter 2, it has been estimated that a human eats approximately 8 kg of soil during a lifetime. Thus, a varied and ample diet will probably protect against trace-metal deficiencies for most of a lifetime. However, the reduction in physical activity, in circulation, and in appetite in later life, may lead to less trace elements being taken in. Thus, it is often advisable to increase the concentrations of such trace metals for older persons, to counteract their lower presence in the smaller diets see Wound Dressings, page 70). 

In general, textiles used in wound-dressing products include fibres, nanofibres, filaments, yarns, and woven/knitted/non-woven and composite materials. 

Textile materials can be used in moist wound management as fibres themselves (advanced fibres such as alginate and chitosan fibres), or conventional/advanced fibres can be modified or coated with various substances such as honey or hydrogels to obtain special properties such as ultra-absorbency, drag release, etc. In general, textiles used in wound-dressing products come in all possible forms, including fibres, nanofibres, filaments, yarns, and woven/knitted/non-woven and composite materials. 

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