Common housefly

The sex attractant of the common housefly is a hydrocarbon with the formula C23H46. On treatment with aqueous acidic KMn04, two products are obtained, CH3(CH2),2C02H and Cb fCB hCX H. Propose a structure. 

The sex attractant given off by the common housefly is an alkene named muscahtre. Propose a synthesis of muscalure starting from acetylene and any alkyl halides needed. What is the IUPAC name for muscalure ... 

This exposure chamber is not restricted to any species of test insect and the extract of tissue suspected of containing a given insecticide may, of course, be prepared in any desired manner. The use of the common housefly, Musca domestica, as test insect and... 

The comparative residual activity of deposits of DDT and dieldrin, using the common housefly as the test insect, is illustrated in Table VIII. For purposes of comparison, both chlordan and aldrin are included in the tabulations. This material is taken from the paper by Kearns, Weinman, and Decker (7). 

Muscalure is the sex attractant of the common housefly (Musca domesticd). 

Alkenes are hydrocarbons with carbon-carbon double bonds. Alkenes are sometimes called olefins, a term derived from olefiant gas, meaning oil-forming gas. This term Introduction originated with early experimentalists who noticed the oily appearance of alkene derivatives. Alkenes are among the most important industrial compounds (see Section 7-6), and many alkenes are also found in plants and animals. Ethylene is the largest-volume industrial organic compound, used to make polyethylene and a variety of other industrial and consumer chemicals. Pinene is a major component of turpentine, the paint solvent distilled from extracts of evergreen trees. Muscalure (cw-tricos-9-ene) is the sex attractant of the common housefly. 

Muscalure, the sex attractant of the common housefly, is cA-tricos-9-ene. Most syntheses of alkenes give the more stable trans isomer as the major product. Devise a synthesis of muscalure from acetylene and other compounds of your choice. Your synthesis must give specifically the cis isomer of muscalure. 

Muscalure, the sex pheromone of the common housefly, can be prepared by a reaction sequence that uses two nucleophilic substitutions. Identify compounds A-D in the following synthesis of muscalure. 

The jS-chloroethylamine derivative (54 R = H, R1 = CH2CH2C1) is active in 1 % concentration in reducing the emergence of adult common houseflies.72... 

Muscalure is the sex attractant of the common housefly. Flies are lured to traps by filling them with fly bait containing both muscalure and an insecticide. Eating the bait is fatal. 

Muscalure, cis-9-tricosene, is the sex-attractant insect pheromone of the common housefly. Give a practical synthesis of this compound from acetylene and straight chain alcohols. 

In yet another structure-activity investigation, Crombie and Denman [80] demonstrated that the synthetic 10-Z isomer corresponding to pipercide, 50(n=4) was more active in bioassays against the common housefly, Musca domesiica, than the natural, all-E amide, both with respect to kill and knockdown. Some parallels to this kind of structure-activity relationship are found also in the aliphatic amide series [80]. 

The availability of the Brookhaven file (56) and studies of receptor-inhibitor complexes (47,50-55) has been helpful in specific studies, but does not reflect the common situation. All major drug and pesticide companies screen thousands of experimental compounds each year against 30-50 or more complex targets, most of which are undescribed. As one example, topical or microspray application of experimental insecticides to the common housefly (Musca domestica) addresses four acetylcollnesterase isozymes in the head and three others from the thorax ( ). Each, on isolation, responds differently to standard organophosphates as measured by and None have been se-... 

In 1984, Mark E. Schroeder and Roger F. Flattum at Shell explored for nithiazine as the example, at which site these nitromethylene insecticides interact to effect their pharmacological activity. In cockroaches, the nicotinic acetylcholine receptor turned out to be the target. [140] In insects, the expression of these receptors is limited to the nervous system. There they reach a density, which is comparable only to the electric organ of the South American electric eel (Electro-phorus electricus). [ 141 ] From ligand displacement studies with nerve cell receptors of the American cockroach (Periplaneta americana), the honey-bee (Apis mellifera) and the common housefly (Musca domestica), the a-subrmit of the receptor became evident as the prime locus of interaction for neonicotinoids. 

The sex attractant of fhe common housefly (Musca domestica) is a 23-carbon alkene with a cis double bond between atoms 9 and 10 called muscalure ... 

Often pheromones are chemically simple compounds— alcohols, esters, aldehydes, ketones, ethers, epoxides, or even hydrocarbons. Two examples are muscalure and bombykol, the sex attractants of the common housefly and the silkworm moth, respectively. 

Propose a synthesis for (Z)-9-tricosene (muscalure), the sex pheromone for the common housefly (Musca domestica), starting with acetylene and haloaUcanes as sources of carbon atoms. 

Carbenes and Carbenoids A common housefly (Musca domestica). Commercially available traps with the attractant muscalure (synthesized via a route using an organometallic compound) combined with a poison are efficient at luring and killing houseflies (Section 15.2B). 

The sex pheromone of the common housefly is cis-9-tricosene, where tricosene is the lUPAC name of a 23-carbon alkene. Draw the condensed formula of this molecule, marketed under the name Muscalure. 

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