Codeine cough syrup

Promethazaine HCl/w Codeine Cough Syrup—codeine phosphate, promethazine HC1 Quad Tann Tablets—carbetapentane tannate, chlorpheniramine tannate, phenylephrine tannate, ephedrine tannate... 

Schedule V—The drug or other substance has (1) a low potential for abuse relative to the drugs or other substances in Schedule IV, (2) a currently accepted medical use in treatment in the United States, and (3) abuse of the drug or other substance may lead to limited physical dependence or psychological dependence relative to the drugs or other substances in Schedule IV. Example codeine cough syrup. 

Let s say that I just purchased 6 fl. oz. of average codeine cough syrup. I read the label and find that every fl. oz. contains ... 

Concerta see Methylphenidate Coties see Codeine Cough syrup see Codeine Cough-X see Dextromethorphan Cozmo s see PCP (phencyclidine)... 

Insom-X see GBL GHB Invigorate see GBL GHB Ionamin see Diet pills Iophen DM NR see Dextromethorphan Ischott see Catha edulis Isobutyl nitrite see Inhalants Isocarboxazid Marplan see Antidepressants Isosorbide see Diuretics Iubulu see Catha edulis J La rocha see Rohypnol La salade see Catha edulis LA turnarounds see Dextroamphetamine Lady see Heroin Lady K see Ketamine Laevoamphetamine see Amphetamines Laudanum see Opium Laughing gas see Nitrous oxide LBJ see PCP (phencyclidine) Leaky bolla see PCP (phencyclidine) Leaky leak see PCP (phencyclidine) Lean (codeine cough syrup) see Codeine... 

Most of us are aware of the big Codeine cough-syrup scare of the early 60 s. All of a sudden, with a history going back to the Civil War, we "discover" a few milder Codeine addicts are still around, and set out to stomp them out via the media. As a result, some heavy anti-cough syrup legislation was created, and millions of people became aware that Codeine existed. Abuse rate shot way up, and to this date we still have... 

A formula for a cough syrup contains 1/8 gr of codeine phosphate per teaspoonful. How many grams of codeine phosphate should be used in preparing two pints of the cough syrup ... 

If a cough syrup contains 0.24 g of codeine in 120 mL, how many milligrams of codeine are contained in each teaspoonful dose ... 

In the United States and other countries, some cough syrups and tablets containing codeine are available without prescription, usually those with less than 10 mg of codeine. Houston, Texas, has been called the city of syrup because of the city s high rates of codeine abuse (see sidebar). In France, 95 percent of the consumption of a codeine-containing cough... 

B. P. Chattopadhyay, J. Chattopadhyay, and P. C. Bose, Application of high pressure liquid chromatography for simultaneous estimation of aminophylline, codeine, ephedrine, and diphenhydramine in cough syrup, Indian Drugs, 22 154 (1984). 

Codeine is a derivative of morphine that is used as an analgesic, narcotic, or antitussive. It was once commonly used in cough syrups but is now available only by prescription because of its addictive properties. The formula of codeine is CigH2iN03 and the pKb is 6.05. Calculate the pH of a 10.0-mL solution containing 5.0 mg of codeine (pKb = —log Kb). 

A codeine-containing cough syrup lists codeine sulfate as a major ingredient instead of codeine. The Merck Index gives C36H44N20 oS as the formula for codeine sulfate. Describe the composition of codeine sulfate. (See Exercise 67.) Why is codeine sulfate used instead of codeine ... 

Fig. 7.15. Analysis of alkaloids in cough syrup after derivatization with dansyl-chloride2 Column Lichrosorb SilOO 10 wm (250x2.8 mm ID), mobile phase diisopropyl ether - isopropanol -cone, ammonia (48 2 0.3), detection UV 254 nm. Peaks 1, Dns-ephedrine 2, noscapine 3, Dns--cephaeline 4, Dns-emetine 5, codeine t, dodecylbenzene. Fluorescence detection witn excitation 360 nm and emission 500-510 nm.

ETHYL MORPHINE This semisynthetic derivate has an ethyl group instead of the methyl in codeine and is used on a large scale in cough syrups. 

Cough syrups with codeine Some pharmacies still allow cough syrups with codeine to be sold over the counter. 

The separation of codeine, chlorpheniramine, and phenylephrine in a cough syrup... 

Muhammad, N. Bodnar, J.A. Quantitative determination of guaifenesin, phenylpropanolamine hydrochloride, sodium henzoate codeine phosphate in cough s5Tups hy high-pressure liquid chromatography. J.Liq.Chromatogn, 1980, 3, 113-122 [simultaneous benzoic acid, codeine, phenylpropanolamine syrup]... 

Schedule V (examples buprenorphine, products containing a low dose of an opioid plus a nonnarcotic ingredient such as codeine -I- guaifenesin cough syrup or diphenoxylate -l- atropine tablets) ... 

It is a synthetie morphine derivative used as an antitussive agent exelusively. It has been reported to possess a eough suppression potency nearly one-half that of codeine. It exhibits no depression of the eentral nervous system, laeks analgesic actions and is free from addiction characteristics, which collectively render it possible for its use in cough syrups meant for infants and children. 

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