Cobalt phthalocyanine resins

We have demonstrated a new class of effective, recoverable thermormorphic CCT catalysts capable of producing colorless methacrylate oligomers with narrow polydispersity and low molecular weight. For controlled radical polymerization of simple alkyl methacrylates, the use of multiple polyethylene tails of moderate molecular weight (700 Da) gave the best balance of color control and catalyst activity. Porphyrin-derived thermomorphic catalysts met the criteria of easy separation from product resin and low catalyst loss per batch, but were too expensive for commercial implementation. However, the polyethylene-supported cobalt phthalocyanine complex is more economically viable due to its greater ease of synthesis. 

Wring, S.A., J.P. Hart, and B.J. Birch (1991). Determination of reduced glutathione in human whole blood by high-performance Iquid chromatography with electrochemical detection by a graphite-epoxy resin electrode chemically modified with cobalt phthalocyanine. Ya/anfa 38(11), 1257-1260. 

Hart, J.P. andl.C. Hartley (1994). Development of amperometric sensors for uric acid based on chemically modified graphite-epoxy resin and screen-printed electrodes containing cobalt phthalocyanine. Analyst 119(2), 259-263. 

In order to decrease the overpotential for cysteine oxidation in cysteine-containing peptides, graphite-epoxy resin or carbon paste electrodes with immobilized cobalt phthalocyanine have been employed in HPLC systems [53,87-89]. Glassy carbon electrodes modified with a mixed-valence ruthenium(I V,III) oxide film stabilized by cyano cross-links [61,62], indium ferricyanide [63], or a Prussian blue film [64], and a bismuth(V)-doped lead dioxide Pb02 film on gold [65] have also been used for detection following HPLC separation. In addition, a carbon fiber modified with a nfixed-valence ruthenium(IV,III) oxide film stabilized by cyano cross-links has been used in CE [46]. 

Deoxynucleosides have been protected at 0-5 by a modified dimethoxytrityl group as in 182 the A -hydroxysuccinimidyl ester permits attachment to resins with pendant amine groups, and the nucleoside can be recovered by mild acid treatment. On the other hand, the l,l-dianisyl-2,2,2-trichloroethyl ether (DATE) protecting group, as in 183, is particularly stable towards both acids and bases, but easily removed by reductive fragmentation using the supemucleophilic lithium cobalt(I) phthalocyanine. ... 

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