Pendant amine

Chen and coworkers were the first to describe the electrochemical behavior of PB NPs [41]. They prepared solutions of PB NPs by reaction of Fe(III) with Fe(CN)6 in the presence of H2O2, giving 30-50-nm diameter NPs. These were then immobilized at cysteine-modified Au electrodes with pendant amine groups by prolonged (10 h) exposure of the modified electrode to a solution of the NPs. This produced a monolayer of immobilized NPs that was subsequently examined using cyclic voltammetry. Interestingly, they observed two redox processes near 0.25 V vs. 

As a simple and practical alternative to coated microspheres, submicron particles of pendant amine-functionalized PPE 39 could be fabricated by phase... 

Finally, Lecomte and coworkers reported the synthesis of mikto-arm star-shaped aliphatic polyesters by implementing a strategy based on click chemistry (Fig. 36) [162]. Firstly, the polymerization of sCL was initiated by a diol bearing an alkyne function. The chain-ends were protected from any further undesired reaction by the esterification reaction with acetyl chloride. The alkyne was then reacted with 3-azidopropan-l-ol. The hydroxyl function located at the middle of the chain was then used to initiate the ROP of sCL and y-bromo-s-caprolactone. Finally, pendant bromides were reacted successfully with sodium azide and then with N, N-dimethylprop-2-yn-l-amine to obtain pendant amines. Under acidic conditions, pendant amines were protonated and the polymer turned out to exhibit amphiphilic properties. 

Formally, the synthetic route outlined in Scheme 6 constitutes the preparation of a new ring system from another. Nucleophilic attack of amine on the sulfonate ester, a particularly good leaving group, leads to monocyclic compound 67. Conversion of the sulfonic acid moiety into a sulfonyl chloride by POCI3 then yields the sulfonyl chloride siVu, which then undergoes nucleophilic attack by the pendant amine resulting in the chiral sultam 68. 

Apparently, the solubility of novolac resin in aqueous base is sufficiently altered by the pendant amine to facilitate image development. 

Chiral 1,2-oxazines (33) have been prepared from achiral ketones, R -CO-CfT-R2, via an a-oximation step (with a tetrazolylpyrrolidine organocatalyst), followed by a Wittig reaction.87 Subsequent N—O cleavage yields enantiopure ds-allylic alcohols bearing a pendant amine. 

Harmon, B.W., Ensor, D.D., Delmau, L.H., Moyer B.A. 2007. Extraction of cesium by a calix[4]arene-crown-6 ether bearing a pendant amine group. Solvent Extr. Ion Exch. 25 (3) 373-388. 

Using a transition state model for enolate formation and a database search, a thiourea with a pendant amine has been designed as a catalyst, and its ability to hydrogen bond the enolate of acetone explored.287 Both in-plane and out-of-plane hydrogen bonds, to a lone a pair and the carbonyl 7r-bond, respectively, were considered. 

The X-ray structure of [Zn2(8-H)F is shown in Pig. 2. The p for the doubly coordinated pendant alcohol is below 4, in accord with corresponding measurements made on water molecules coordinated to a pair of Zn(II) ions in a cyclic octaamine (<7) 22), or in a cyclic tetraamine with four pendant amines (<5.3) 23). On reaction with 4-nitrophenyl phosphate, 4-nitrophenol is released and a complexed phosphoramide is produced, [Zn2(9)] +, resulting from attack of a secondary amine at phosphorus. 

Metalation of RR SbH with BuLi gives the chiral lithium antimonide RR SbLi [R = 2-(Me2NCH2C6H4, R = CH(SiMe3)2] (4) that forms RR SbNa after transmetalation with BuONa in the presence oftetramethylethylenediamine. The pendant amine arm of (4) is coordinated to the alkali metal center. 

The ligand L3 was initially intended to provide enforced tetrahedral coordination at the metal. Moore and co-workers (30,31) have successfully used the pendant arm macrocycle L5, also a derivative of [12]aneNs, for the same purpose (although in view of the foregoing discussion, enforcing the geometry may not have been necessary). The three macrocyclic nitrogen donors form the base of a tetrahedron and the pendant amine fills the apical site. If the pendant arm is shorter. 

For instance, in the functionalized macrocycle 2 the donor atom of the ethylamine pendant arm is a primary, rather than a tertiary, amine nitrogen atom, which gives rise to a stronger axial interaction with the metal. In fact, the pKA of the pendant amine group in the [Ni(II)-(2)]2+ complex, 2.8, is much lower than observed for the corresponding complex of 1. Noticeably, in the... 

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