Etoposide Cisplatin

Bremnes RM, Sundstrom S, Aasebo U, Vilsvik J. Paclitaxel in combination with cisplatin, etoposide and thoracic radiotherapy for limited stage small cell lung cancer (SCLC) a phase II study (abstract 1826). ProAmSoc Clin Oncol 1998 17 475a. 

The RT consisted of 45 Gy in 3 wk using 1.5 Gy bid concurrent with either cisplatin/etoposide or carboplatin/vindesine after the same drugs had been given alone at higher dosage. Acute toxicity was acceptable and treatment-related deaths were 9% or... 

CAV = cyclophosphamide/doxorubicin/vincristine CEV = cyclophosphamide/epirubicin/vincristine CCM = cyclophosphamide/lomustine/methotrexate EA = etoposide/doxorubicin VMV/VAC = vincristine, methotrexate, VP-16/vincristine, doxorubicin, cyclophosphamide VAP = vincristine/doxorubicin/ procarbazine PE = cisplatin/etoposide. 

IEP = ifosfamide, etoposide, cisplatin PEP = cisplatin, etoposide, paclitaxel EP = etoposide + cisplatin TP = topotecan+ paclitaxel E Carbo = etoposide + carboplatin. 

Ettinger DS, Seiferheld WF, Abrams RA, et al. Cisplatin, etoposide, paclitaxel and concurrent hyperfractionated thoracic radiotherapy for patients with limited disease small-cell lung cancer Preliminary results of RTOG 96-09 (abstract 1917). Proc Am Soc Clin Oncol 2000 19 490a. 

Intracavitary administration of various agents has been used for patients with malignant pleural or peritoneal effusions. Intraperitoneal instillations of cisplatin, etoposide, bleomycin, 5-fluorouracil, and interferon are well tolerated and are being evaluated in patients with ovarian carcinomas, in whom the tumor is frequently restricted to the peritoneal cavity. 

A 31-year-old man with a seminoma had an orchidect-omy, followed by chemotherapy with cisplatin, etoposide, and bleomycin (92). A day after the end of the second course of chemotherapy he became comatose with a heart rate of 150/minute and a systolic blood... 

TR is a 24-year-old man with testicular cancer who is about to receive a combination of cisplatin, etoposide, and vinblastine. Which factor(s) should be considered prior to administration of the vinblastine ... 

Mavroudis D, Papadakis E, Veslemes M, et al. A multicenter randomized clinical trial comparing paclitaxel-cisplatin-etoposide versus cisplatin-etoposide as first-line treatment in patients with small-cell lung cancer. Ann Oncol 2001 12 463 70. 

Williams S, Blessing JA, Liao SY, et al. Adjuvant therapy of ovarian germ cell tumors with cisplatin, etoposide, and bleomycin A trial of the Gynecologic Oncology Group. J CUn Oncol 1994 12 701-706. 

Sodium valproate Phenytoin Cisplatin Etoposide Bleomycin Testicular cancer Serum valproate levels reduced by 50% after the first cycle and generalised tonic-clonic seizures occurred. There was no effect on phenytoin levels. 13... 

The effects of cisplatin, etoposide and irinotecan on neuroblastoma cell lines and neuroblastoma xenografts have been assessed with H NMR. Cytotoxic drug treatment of sensitive cells resulted in increased methylene and polyunsaturated fatty acid resonances and decreased choline resonances the... 

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