Chronic Respiratory Questionnaire

Unfortunately, most treatments for COPD have not been shown to improve survival or to slow the progressive dechne in lung function. However, many therapies do improve pulmonary function and quality of hfe and reduce exacerbations and duration of hospitalization. Several disease-specific quahty-of-life measures are available to assess the overah efficacies of therapies for COPD, including the Chronic Respiratory Questionnaire (CRQ) and the St. George s Respiratory Questioimaire (SGRQ). These questionnaires measure the impact of various therapies on such disease variables as severity of dyspnea and level of activity they do not measure impact of therapies on survival. While early studies of COPD therapies focused primarily on... 

To increase the level of sensitivity to an impairment in health status, disease-specific questionnaires have been developed. The Chronic Respiratory Questionnaire (CRQ) (12)... 

Abbreviations-. TCEMS, transcutaneous electrical muscle stimulation CHF, congestive heart failure COPD, chronic obstructive pulmonary disease Vo2max, peak oxygen consumption NYHA, New York heart association CSA, cross-sectional area Wmax, maximal workload CRQ, chronic respiratory disease questionnaire. 

Jones PW, Quirk FH, Baveystock CM, et al. A self-complete measure for chronic airflow limitation. The St George s Respiratory Questionnaire. Am Rev Respir Dis 1992 145, 1321-1327. Wegner RE, Torres RA, Kirsten DK, et al. Factor analysis of exercise capacity, dyspnoea ratings and lung function in patients with severe COPD. Eur Respir J 1994 7 725-729. 

There are no reported sequelae in ODTS. However, long-term follow-ups are needed. Extensive investigations have revealed no effects in respiratory function, gas exchange or exercise capacity in farmers who have experienced ODTS, in some cases repeated attacks (Malmberg et al. 1985) neither does grain fever lead to fibrosis or permanent disability (Manfreda and Warren 1984). However, in Finland, farmers wives who had experienced ODTS had more chronic bronchitis than others (Husman et al. 1990). Also, in a questionnaire study of 7496 farmers from four European countries, ODTS was a major predictor of chronic bronchitis (Radon et al. 2003). Prospective studies on the association between ODTS and COPD and other chronic respiratory symptoms are needed. 

Holness et al. (1989) compared effects in a group of 58 workers chronically exposed to ammonia vapor (9.2 1.4 ppm, mean standard deviation) with the effects in a group of plant workers who had no exposure to ammonia (0.3 0.1 ppm, mean standard deviation). During a 1-wk period, the workers were assessed, based on a questionnaire, on sense of smell and respiratory function. There were no reported differences between the two groups. 

Respiratory Effects. Physical examination of library workers acutely exposed to high but unquantified concentrations of chlordane from a spill revealed no indication of respiratory effects (NIOSH 1984a). Chest pains, dyspnea, and shortness of breath were reported in a compilation of cases and personal reports of humans accidentally exposed to chlordane by inhalation (EPA 1980a) exposures frequently involved a mixture of chemicals (such as other related and nonrelated pesticides) and vehicles (including petroleum distillates). Therefore, these effects cannot be attributed to chlordane alone. Results of a questionnaire indicated increases (compared with the National Center for Health Statistics 1979 National Health Interview Survey) in sore throat and respiratory infections in humans shortly after their homes were treated for termites (Menconi et al. 1988). Chronic exposure in pesticide treated homes was associated with bronchitis and sinusitis. 

Medical Research Council. Committee on research into chronic bronchitis. Instructions for use of the questionnaire on respiratory symptoms. In Devon LW, ed. Holman, 1966. 

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