Chronic obstructive pulmonary disease case study

Some studies of survivors of massive chlorine exposures have shown either persistent obstructive or restrictive deficits, but pre-exposure data on these patients were not available. Persistent respiratory symptoms, bronchial obstruction, and bronchial hyperresponsiveness were observed in 82%, 23%, and 41 % of chronically exposed pulp mill workers, respectively, 18-24 months after cessation of exposure." In most cases it is not known whether prolonged symptoms after chlorine exposure are due to aggravation of preexisting conditions such as tuberculosis, asthma, chronic obstructive pulmonary disease, or heart disease." "... 

Case study level 3 - Chronic obstructive pulmonary disease (COPD) - with co-morbidity... 

Case study level 2 - Puffing away makes you lose your puff treatment of chronic obstructive pulmonary disease... 

Soraya Dhillon and Andrzej Kostrzewski Case study level 1 - Asthma - community 49 Case study level 2 - Asthma - acute on chronic 50 Case study level 3 - Chronic obstructive pulmonary disease (COPD) -with co-morbidity 52 Case study level Ma - COPD 54 Case study level Mb - Brittle asthma 56... 

Watson L, Margetts BM, Howarth P, et al Do dietary factors protect against chronic obstructive pulmonary disease A case control study. Am J Respir Crit Care Med 2001 163 A40. 

A study in 17 patients with chronic obstructive pulmonary disease found that nizatidine 150 mg twice daily for a month had no effect on the steady-state pharmacokinetics of theophylline. However, there were 6 reports of apparent interactions in the Spontaneous Adverse Drug Reaction Database of the FDA in the US up to the end of August 1989. Four patients taking theophylline developed elevated serum theophylline levels, with symptoms of toxicity in at least one case, when given nizatidine. The problems resolved when either both drugs, or just nizatidine were stopped. ... 

Wang MT, Tsai CL, Lo YW, Liou JT, Lee WJ, Lai IC. Risk of stroke associated with inhaled ipratropium bromide in chronic obstructive pulmonary disease a population-based nested case-control study. Int J Cardiol July 12, 2012 158(2) 279-84. 

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