Chlorphenamine maleate

Common Name Chlorophenyl pyridyl propyidimethylamine maleate chlorphenamine maleate chlorprophen-pyridamine maleate... 

A 71-year-old Japanese man developed an itchy erythematous papular eruption after using an over-the-counter medicament for skin wounds (Makiron) for 1 month (34). Patch tests with the constituents showed positive reactions to dl-chlorphenamine maleate and cinchocaine hydrochloride (both 1% in petrolatum). Patch tests with lidocaine hydrochloride and mepivacaine hydrochloride showed no cross-sensitization. 

In some oral formulations yellow wax is used as a polishing agent for sugar-coated tablets. It is also used in sustained-release formulations. Yellow wax coatings can be used to affect the release rate of drug from ion-exchange resin beads, and has also been used in multiparticulate controlled-release dosage forms of chlorphenamine maleate. ... 

B Yang, J Mo, X Yang, L Wang. Separation and determination of chlorphenamine maleate, acetaminophen and vitamin C of cold medicines by capillary electrophoresis with amperometric detection. Sepu 17 477-479, 1999. 

Piriton (Chlorphenamine maleate), GlaxoSmithKline ConsumerHealtiicare. UK Summary of product characteristics, October 2004. 

An 89-year-old man who had used over-the-counter topical antiseptics developed pruritic lesions over his left knee after using a topical medication containing benzalkonium chloride, dibucaine hydrochloride, chlorphenamine maleate, naphazoline hydrochloride, and a mixture of fragrance ingredients. There were pruritic erythematous papules and vesicles over the knee, and linear extensions down the lower leg appeared the next day. The dermatitis was successfully treated with topical glucocorticoids. Subsequent patch testing of the over-the-counter antiseptic was positive. 

The authors diagnosed allergic contact dermatitis to dibucaine hydrochloride, chlorphenamine maleate, and naphazoline hydrochloride, although none of these was patch tested in isolation. They speculated that sensitization to these three agents had occurred sequentially during previous exposures to the topical antiseptic. 

Chlorphenamine maleate tablets 4 mg, oral solution 2 mg/5 mL, injection 10 mg/mL Clemastine hydrogen fumarate tablets 1 mg... 

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