Cinchocaine hydrochloride

Common Name Cincaini chloridum Cinchocaine hydrochloride ... 

A 71-year-old Japanese man, who was using an over-the-counter formulation, Makiron, for minor wounds, developed an itchy rash with seropapules and erosions on his right leg at the site of application (5). Makiron contains 0.1% cinchocaine hydrochloride and chlorphe-namine maleate as well as naphazoline hydrochloride and benzethonium chloride. On patch testing, he was positive to both chlorphenamine and cinchocaine. 

A 71-year-old Japanese man developed an itchy erythematous papular eruption after using an over-the-counter medicament for skin wounds (Makiron) for 1 month (34). Patch tests with the constituents showed positive reactions to dl-chlorphenamine maleate and cinchocaine hydrochloride (both 1% in petrolatum). Patch tests with lidocaine hydrochloride and mepivacaine hydrochloride showed no cross-sensitization. 

A 23-year-old woman developed an allergic contact dermatitis after applying an over-the-counter proprietary antipruritic jelly containing 0.1% cinchocaine chloride, and a caine mixture (5% benzocaine, 1% cinchocaine hydrochloride, 1% procaine hydrochloride) (39). She had positive patch testing to both components. 

A. Dibucaine Hydrochloride USAN, Cinchocaine INN, Cinchocaine Hydrochloride BAN,... 

Butoxy-N-[2-(diethylamino)-ethyl]-, monohydrochloride 4-Quinolinecarboxamide, 2-butoxy-N-[2-diethylamino)-ethyl]-, monohydrochloride U.S.P., N.F., Cinchocaine Hydrochloride B.P.,... 

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