Chemical peels glycolic acid

Side effects, such as temporary hyperpigmentation or irritation, are not very significant. Finally, glycolic acid is a member of the alpha-hydroxy acid family, which provides an important adjunctive therapy in a variety of skin disorders. It is widely used in chemical peels in a variety of concentrations, ranging from 20% to 70%. People of almost any skin type and color are candidates and almost any area of the body can be peeled. Glycolic acid can be applied simultaneously with TCA, which represents another technique for a... 

Fig. 4.20 Diffusion of products for chemical peeling (glycolic add and trichloroacetic acid)...

Salicylic acid is a beta hydroxy acid. Glycolic acid is an alpha hydroxy acid, as are lactic acid, citric acid, and many others. Hydroxy acids are compounds that are both alcohols and acids at the same time. Hydroxy acids are used as chemical peeling agents. Alpha hydroxy acids can make the skin more sensitive to ultraviolet light by removing the skin s protective outer layers. Some alpha hydroxy acids ... 

Glycolic acid Jessner s solution Pyruvic acid Resorcinol Salicylic acid Trichloracetic acid Deep chemical peels... 

In patients with acne (Fig. 2.4), the chemical peels were performed with a 70% glycolic acid solution, for 2 to8 min. The number and frequency of the applications depended on the intensity of the clinical response. The most rapid improvement was observed in comedonic acne, in the papulo-pustular forms. An average of six applications were necessary (Fig. 2.5a, b). 

Hematoxylin/eosin stains of biopsies of back skin taken 24 h post-chemical peeling, a Glycolic acid peel 70%. Note stratum corneum necrosis... 

Tretinoin 1% has also been used as a chemical peeling agent [22,23]. The efficacy of tretinoin peels was compared with glycolic acid peels in the treatment of melasma in dark skinned patients [23]. In a split face study of ten Indian women, 1% tretinoin was applied to one half of the face, while 70% glycolic acid was applied to the opposite side. Peels were performed weekly. Significant improvement occurred on both sides as assessed by photographs and a Modi-... 

Superficial chemical peels, including salicylic and glycolic acids, and Jessner s peels target the stratum corneum to the papillary dermis. These agents can be safely used to facilitate the resolution of PIH (Figs. 16.2,16.3,16.4 and 16.5). To assess for variability in response and limit further PIH, when possible, chemical peels should be initiated at the lower concentrations and titrated to higher concentrations if necessary to increase efficacy while minimizing side effects (see Darker Skin Section). 

Song, J.Y., et al. 2004. Damage and recovery of skin barrier function after glycolic acid chemical peeling and crystal microdermabrasion. Dermatol Surg 30 390. 

Moy LS, Mene R. Glycolic acid chemical peel. In Roenigk Roenigk s Dermatoligic Surgery, Principles and Practice, 2ndedn. 1103-12. 

Through the patient s history and physical examination, the physicians will identify any specific factor such as medications, prior procedures, and medical conditions that can affect the outcome of the peel [17]. Complications of glycolic acid peel Uke hyperpigmentation and infection are rare. Chemical peel with glycolic acid may cause sensible irritation symptoms, characterized by stinging, burning, and itching. 

Superficial peels Various chemicals have been used as peeling agents, out of which the most fruitful one is the alpha-hydroxy acid such as glycolic acid. Alpha-hydroxy acid (AHA) works inducing epidermolysis and subsequent desquamation within few... 

Grimes [11] compared the histologic alterations induced by a variety of chemical peels in 17 patients with skin types IV, V, and VI, including glycolic acid 70%, salicylic acid 30%, Jessner s solution, and 25% and 30% TCA. Peels were applied to 4 x 4 cm areas of the back and 2 x 2 cm postauricular sites. Biopsies were performed at 24 h (Fig. 21.2a-d). Glycolic acid induced the most significant stratum comeum necrosis. Compared to the other tested peels, salicylic acid and Jessner s peels caused mild lymphohistiocytic der-... 

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