Chemical compatible groupings

The Cadila system [13] has been designed to formulate tablets for drugs based on their physical (solubility, hydroscopicity, etc), chemical (functional groups), and biologically interrelated (dissolution rate) properties. The system first identifies the desirable properties for optimum compatibility with the drug, selects those excipients that have the required properties, and then recommends proportions based on the assumption that all tablet formulations comprise at least one binder, one disintegrant, and one lubricant. Other... 

Explosives, See also Explosive chemicals Transportation carriage, 447, 460, 594 compatibility groups, 456 hazard classification, 447, 455 Exposure limits. See Hygiene standards Eye protection, 435... 

If chemical-specific information is not available, the consequences may be able to be predicted by methods using compatibility groups, or chemicals with similar chemical structures that are expected to have similar chemical reactivity characteristics. One computerized tool that uses this approach is the Chemical Reactivity Worksheet made available by the U.S. National Oceanic and Atmospheric Administration (NOAA 2002). This program has over 6000 chemicals, mixtures, and solutions included in its database. It also predicts chemical reaction consequences of combining two materials at a time (e.g., "Heat generation by chemical reaction, may cause pressurization"). Examples from the Chemical Reactivity Worksheet are shown in Section 4.2. It is critical that all chemicals be positively identified to have a complete evaluation of all potential incompatibilities. 

Any one of the three components in SOFC, the cathode, anode, or electrolyte, can provide the structural support for the cells. Traditionally, the electrolyte has been used as the support however, this approach requires the use of thick electrolytes, which in turn requires high operating temperatures. Electrode-supported cells allow the use of thin electrolytes. The Siemens—Westinghouse Corporation has developed a cathode-supported design,although this has required electrochemical vapor deposition of the YSZ electrolyte. Most other groups have focused on anode-supported cells. In all cases, it is important to maintain chemical compatibility of those parts that come in contact and to match the thermal expansion coefficients of the various components. A large amount of research has been devoted to these important issues, and we refer the interested reader to other reviews. 

Compatibility Group G comprises any substance which is an explosive substance because it is designed to produce an effect by heat, light, sound, gas or smoke, or a combination of these as a result of non-detonative, self-sustaining, exothermic chemical reactions, or an article containing such a substance or an article containing both a substance which is explosive because it is capable by chemical reaction in itself of producing gas at such a temperature and pressure. 

Chemical Compatibility Classification — The U.S. Coast Guard defines 43 cargo groups listed in Navigation and Vessel Inspection Circular No. 4-75, "Guide to Compatibility of Chemicals."... 

A solid-phase Ugi-Reissert reaction on chloroformate resin, has been reported. The product, the ot-carbamoylated isoquinoline 230, is released by oxidative cleavage (Scheme 33a). Interestingly, the enamide moiety in the adduct can be exploited to perform this process in tandem with a Povarov MCR [189, 190]. In this way, by interaction of dihydroisoquinoline 231 with aldehydes, anilines and a suitable Lewis acid catalyst, the polyheterocyclic system 232 was prepared (Scheme 33b). The Zhu group devised an innovative approach for the synthesis of this class of compounds. They employed the heterocyclic amine 233, which was oxidized in situ to the dihydroisoquinoline 234 with IBX, to undergo the classic Ugi reaction. Remarkably, all the components are chemically compatible, allowing the sequence to proceed as a true MCR (Scheme 33c) [191]. 

Recently, one more Ti precursor has been introduced, Ti(MPD)(thd)2 (MPD = methyl-pentanedioxide), but its effects on the BST film deposition are not yet well known. It is generally understood that the optimum Ti precursor must have chemical compatibility with the Ba and Sr precursors, such as non-interaction in solution or in the gas phase and similar decomposition characteristics to the Ba and Sr precursors, in addition to volatility. Most of the Ti precursors discussed above have much better volatilities and thermal stabilities than those of the precursors of the group II elements but are still lacking appropriate chemical compatibility with them. It is known that the thermal decomposition of Ti(thd)2(i-0-P )2 is quite different from that of the Ba(thd)2 and Sr(thd)2 from the increasing Ti concentration in the BST film with increasing temperatures.It is believed that the thermal decomposition of Ti(thd)2(i-0-P )2 requires more... 

Given the many forms or structures in which hydrocarbons can occur, along with the fairly broad number of substituent groups that can be attached onto or into them, it is apparent that an almost limitless variety of explosive compounds are possible. Of this almost limitless variety, surprisingly few are commonly used. The number is severely limited by several factors. The cost of raw materials and processing is one of the major factors. Thermal stability, chemical compatibility, toxicity, physical form, handling sensitivity, and explosive output prop-... 

Chemicals to be transported must be packaged by the compatibility group and must comply with packaging and transportation requirements (LIR 405-10-01.0, Packaging and Transportation ). Containers that have explosives in them must comply with the requirements contained in the DOE Explosives Safety Manual and the packaging and transportation LIR. Federal DOT regulations in 49 CFR Parts 171-178 provide the guidance for transport, classification, and inspections of cylinders. 

Separate chemicals into compatible groups and store alphabetically within corr5)atible groups. See Table 4.1 for one suggested method for arranging chemicals in this way. 

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