Changing facilities

Make sure that there are adequate washing and changing facilities. 

Sensitive balance with the sample pan inside a furnace whose temperature can be accurately controlled and programmed for change. Facilities for... 

Sometimes in the design of a BSL-4 facility, the full letter of health and safety codes/requirements for the protection of workers can not be met. This is where health and safety specialists must compromise and use their ingenuity to meet the intent of the requirements. For example, it is not always possible to provide a secondary means of egress from each area. Two change facilities are not cost effective or practical. A viable alternative is the use of airlocks with built-in liquid disinfection systems which are not hazardous to humans, but destroy the biohazard. These airlocks must be clearly identified as others are often used for transportation of equipment and other materials and contain hazardous disinfection systems. 

Laboratory rooms intended for toxic work should be provided with adjacent shower and change facilities. The layout must not require freshly showered personnel to track back through the area that they might have just contaminated. All drains, including those in laboratory floors, should have deep traps and be directed to a toxic sump. Airlocks will help prevent toxic fumes from spreading to non-toxic areas in the event of a failure of a primary containment cabinet. Check valves in the incoming water lines will prevent contamination of potable water supplies when pressure is lost. 

Changing facilities operations Change/locker rooms and showers contiguous with work area for production, maintenance, service and personnel decontamination for production and pilot plant-scale operation (e.g., greater than 5 kg powder or 100 L liquid). Access to change/locker space and showers required for kilo and small-scale operations (e.g., less than production and pilot plant scale)... 

The second-level supervisor or department head ensures that PSSR requirements have been addressed and documented in the PSSR Form. He may elect to secure additional approvals. His authorization signature (line 9) grants approval to start up the new or changed facilities. If any of the pre-startup requirements have not been met satisfactorily, he notifies the supervisor of the affected process unit to correct the deficiencies and repeat the Pre-Startup Safety Review. (Note Authorization to proceed with the change, completion of the PSSR, and approval for startup may occur at the same time for changes of a minor nature.)... 

The average architect will never or very seldom encounter severe corrosive exposures in his practice. He will more likely encounter the so called milder exposures, such as food manufacturing, food preparation, food serving and dairy product processing. Involved with these are the cleanup areas, i.e., sterilizing processes. The correct design of an area which will not harbor contaminants is important. The architect will also become involved in public toilets as well as employee toilets and change facilities. 

The health status of animals from which starting materials are derived and of those used for quality control and safety testing should be monitored and recorded. Staff employed in animal quarters must be provided with special clothing, changing facilities and showers. Where monkeys are used for the production or quality control of biological products, special consideration is required, as laid down in the revised Requirements for Biological Substances No. 7 (Requirements for Polio-myelitis Vaccine (Oral))(5). 

Staff employed in such areas must be provided with special clothing and changing facilities. 

All filters in isolators in which hazardous substances are handled must have a safe change facility. Both the manufacturer and the user should be made aware of the risks associated with changing filters. 

A variety of fraction collectors are available from a number of manufacturers and include those which are able to collect low microlitre volumes in addition to those used in preparative HPLC which can collect much larger volumes. Fraction collectors which are to be used with HPLC systems require very rapid tube changing facilities and should also be resistant to the solvents used with HPLC systems thus, fraction collectors which are designed for use with low pressure chromatography are usually inadequate. A major feature in the more recently marketed fraction collectors has been the introduction of advanced microprocessor control which provides a number of capabilities ranging from simple timed collection to total integrated control of the whole HPLC system. 

Employees will use their ID card to pass through the reception area into more secure areas. This zone contains offices of the laboratory director and support staff, technical staff workstations and meeting space. Bathroom, shower and change facilities appropriate to the size and amenities of the facility should be located in this area. Kitchen and dining space should be provided here because eating and drinking are not allowed inside any laboratory work area. 

The entire laboratory work area is the higher-security zone. Entry into the laboratory should be limited on a need to be there basis. Direct access to and from the laboratory should be minimized. The shower and change facility constitutes a buffer area for transit from the main laboratory to the administrative area, as shown in Fig. 13.3. 

Conditions in the damaged reactor building may be so hazardous that progress will be slow and backup teams will be required so as to limit radiation dose commitments to the individual teams. Teams returning to base may be heavily contaminated and will require substantial clean-change facilities near the ICC. 

Store personal protective equipment in the changing facilities... 

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