Vaginal carcinoma

Tamoxifen -nonsteroidal antiestrogen -nausea and vomiting -bowel changes (diarrhea or constipation) -headache -peripheral edema -hot flashes -endometrial carcinoma -vaginal bleeding -venous thrombosis... 

The presence of human papilloma virus (HPV) is associated with female genital tract diseases such as condyloma, Bowenoid papulosis, and cervical, vaginal, and vulvar intraepithelial neoplasia and carcinoma. A general concern is the association of HPV with cervical cancer (Gl). The HPV consists of an icosahedral viral particle (virion) containing 8000 base pairs, a circular, double-stranded piece of DNA surrounded by a protein capsid. Viral replication takes place within the nuclei of infected squamous epithelial cells (H5). Following infection of epithelial cells, the viral DNA penetrates throughout the entire thickness of the epithelium, but intact viruses are found only in the upper layers of tissue. 

In women with lower-genital-tract carcinomas—cervical, vaginal, and vulvar carcinomas—hematogenous metastases are rarely present at diagnosis, and thus disease can frequently be controlled with local treatment. Small tumors can usually be treated with surgery alone, but cancers that penetrate deeply, particularly those that involve adjacent... 

Prolonged administration increases the risk of gallbladderdisease, thromboembolic disease, and breast, cervical, vaginal, endometrial, and hepatic carcinoma. 

Prolonged administration mayincrease the risk of breast, cervical, endometrial, hepatic, and vaginal carcinoma cerebrovascular disease, coronary heart disease, gallbladder disease, and hypercalcemia. 

Atrophic vaginitis, female castration, female hypogonadism, kraurosis vulvae, menopausal symptoms, primary ovarian failure, prostatic carcinoma IM Initially, 0 1 or0 5... 

It is estimated that in the USA, the Netherlands, and France, diethylstilbestrol was given to over 5.3 million pregnant women, and it is known that it has been given to pregnant women in most parts of the world. Single cases of clear-cell vaginal carcinoma from many countries are known, but systematic studies have not been conducted everywhere. 

Estrogens are contraindicated in patients with estrogen-dependent neoplasms such as carcinoma of the breast or endometrium. Vaginal adenocarcinoma has been reported in young women whose mothers were treated when pregnant with them with diethylstilbestrol in an effort to prevent miscarriage. 

However, it is important to bear in mind that cases occur in which there is no history of the mother s having taken diethylstilbestrol during pregnancy. In one such case, HIV/AIDS infection was also a predisposing factor for vaginal carcinoma and this could explain a proportion of new cases that are being reported today (35). 

Adenocarcinoma, thyroid (note 100 anaplastic carcinomas of thyroid are less frequently positive) Carcinoma, small cell, vaginal 34... 

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