Carcinogens precautions

Properties Colorless/strawyel. spherical beads all pass 8 mesh screen odorless tasteless sol. in many org. soivs. insol. in water m.w. 90,000 dens. 1.19 g/cc (20 C) vise. 10-12 cps soften, pt. 130 10 C tens. str. 5000 psi max. sp. heat 0.39 cal/g/°C 98.5% min. solids 1.5% volatiles Toxicoiogy TWA 10 mg/m nuisance dust may cause mech. eye irritation contains < 0.5% vinyl acetate monomer, suspected carcinogen Precaution Incompat. with oxidizing agents reaction with peroxide may result in a violent decomp, and explosion Hazardous Ingredients Vinyl acetate monomer (< 0.5%)... 

Properties Dens. 0.980 tens. str. 1000-3000 psi elong. 100-700% Toxicology Suspected carcinogen Precaution Combustible... 

Toxicology ACGIH TWA 0.5 mg(Cr)/m toxic by inh., ing., skin contact irritating to eyes, skin, respiratory system possible risk of irreversible effects possible carcinogen Precaution Avoid strong oxidants Hazardous Decomp. Prods. Irritating and toxic fumes and gases... 

LD50 (IP, mouse) 209 mg/kg poison by IP route inh. causes human blood and Gl system effects possible carcinogen Precaution Flamm. when exposed to heat or flame explosion risk in contact with oxidizers mod. explosive by spontaneous reaction with chlorates, perchlorates, CIO reacts with water or steam to produce toxic/flamm. vapors Hazardous Decomp. Prods. Heated to decomp, or on contact with acid or acid fumes, emits... 

Properties Deep red cryst. sol. in alkali hydroxides very si. sol. in hot CS2 and benzene pract. insol. in water m.w. 427.95 dens. 3.5 m.p. 320 C b.p. 565 C Toxicology Poison carcinogen Precaution Ignites at high temps. dec. by HNO3 Hazardous Decomp. Prods. Heated to decomp., emits As, SOx... 

Toxicology May cause skin, nasal passage, respiratory tract irritation, and severe eye irritation can be absorbed thru skin a solvent (formaldehyde) in this compd. is a carcinogen Precaution Flamm. liq. UEL 7.0% incompat. with strong oxidizing agents Hazardous Decomp. Prods. Heated to decomp., emits toxic fumes of CO, CO2, various hydrocarbons... 

Toxicology TDLo (oral, mouse, 65 wks continuous) 1640 g/kg suspected carcinogen Precaution Probably combustible Storage Store under ambient temps. 

Whether OSHA, NTP, or lARC lists the ingredient as a carcinogen Precautions for safe handling and use... 

Toxicology LD50 (orai, rat) > 5 g/kg severe eye irritant may cause si. skin irritation inh. may cause headache, discomfort, irritation of upper respiratory tract ing. may cause diarrhea, weakness, dizziness, headache not listed as a carcinogen Precaution Wear neoprene or rubber gloves, chemical safety goggles with side shields avoid breathing vapors, mists Hazardous Decomp. Prods. CO, hydrocarbons Storage Avoid extreme temps, keep containers closed when not in use keep away from excessive heat, flame Lumisolve CSA-70 [Lambent Tech.]... 

Liquid crystalline compounds are not very dangerous and only basic precautions should be used in handling them. They are not poisonous or carcinogenic, and do not cause problems when in contact with skin (see also Biphenyls and terphenyls Cinnamic acid Stilbene dyes). 

C using a dehydration catalyst consisting of alurninosihcate, Al O, or siUca gel (45). 1-Naphthaleneamine is also toxic (LD q (dogs) = 400 mg/kg) and a suspected human carcinogen, which conditions mandate that appropriate precautions be followed in manufacture and use. 

Suitable precautions should be taken in utilizing this procedure, since substantial quantities of the volatile, known carcinogen, chloromethyl methyl ether, as well as the volatile and flammable methyl chloride, form under the reaction conditions. While intermediates like 15 and 16 have been postulated in a number of publications and patents in this area, no experimental evidence has been reported that describes the presence or foimation of detectable quantities of these species. 

A Michaelis-Arbusov rearrangement followed by a Wittig-Horner reaction is involved in preparation of the distyrylbenzene derivative 11.37, as shown in Scheme 11.15. Precautions must be taken in the first stage to minimise formation of the carcinogenic by-product bis(chloromethyl) ether 11.16. The stilbene bis-ester 11.38 can be made by a similar procedure, or alternatively by the reaction of ethyl acrylate with 4,4 -dibromostilbene in the presence of a palladium-based catalyst (Scheme 11.16), a synthesis that yields the required trans form of the brightener. 

Universal precautions training that complies with the OSHA standard on occupational exposure to bloodborne pathogens, as well as a fire training program, should be provided on an annual basis for all laboratory employees. Personnel are required to use proper personal protective devices when handling corrosive, flammable, biohazard, or carcinogenic substances. Eye wash sta-... 

Dichloromethyl methyl ether (98%) was purchased from Aldrich Chemical Company, Inc. (listed as a, a-dichloromethyl methyl ether), and used without purification. Better results can be obtained if the material is distilled under nitrogen prior to use. Unlike chloromethyl methyl ether and bis(chloromethyl) ether, dichloromethyl methyl ether is reported to have no significant carcinogenic activity.6 However, as a precaution it should be handled carefully in a well-ventilated hood. 

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