Carcinogen list

A super list of world-wide sources of information about drugs, pesticides, environmental pollutants and other potential toxins. Ties into ASDTR, EPA, the National Toxicology Program Carcinogen List (NTPA), and other governmental... 

American Conference of Governmental Industrial Hygienists Carcinogens List... 

National Institute of Occupational Health and Safety Carcinogens List (NIOSH)... 

National Institute for Occupational Safety and Health (NIOSH) Carcinogen List... 

Butadiene is a colorless, odorless, flammable gas, with a bp of -4.7°C. As of 2000 butadiene has been on the Known to Be a Human Carcinogen list of the Department of Health and Human Services. It has a time-weighted average threshold limit value (TLV) of 2 ppm. TLVs and carcinogens will be discussed more fully under benzene. Butadiene is expensive to store because it polymerizes easily and must be refrigerated. 

Benzene is a clear, colorless, flammable liquid with a pleasant characteristic odor, bp 80.1°C, flash point -11.1°C, and ignition temperature 538°C. Benzene has been found to be very toxic and is on the list of Known to Be Human Carcinogens published every two years by the Department of Health and Human Services under the National Toxicology Program (NTP). There are four top 50 chemicals on this worst carcinogen list benzene 1,3-butadiene ethylene oxide and vinyl chloride. There are also four chemicals in the top 50 on the Reasonably Anticipated to Be Human Carcinogens list acrylonitrile, ethylene dichloride, formaldehyde, and propylene oxide. 

We have already been introduced to polyurethane chemistry in Chapter 10, Section 2, where we used toluene diisocyanate (TDI) reacting with a diol to give a polyurethane. Polyurethanes derived from MDI are more rigid than those from TDI. New applications for these rigid foams are in home insulation and exterior autobody parts. The intermediate MDA is now on the Reasonably Anticipated to Be Human Carcinogens list and the effect of this action on the market for MDI remains to be seen. The TLV-TWA values for MDA and MDI are some of the lowest of the chemicals we have discussed, being 0.1 and 0.005 ppm respectively. 

High doses of DEHP have been found to cause liver cancer in rats and mice and it is on the Reasonably Anticipated to Be Human Carcinogens list. In 2000 a report by the National Toxicology Program found serious concern that DEHP in vinyl medical devices may harm the reproductive organs of critically ill and premature male infants exposed during medical treatment. They also expressed concern that development of male unborn babies would be harmed by the pregnant mothers exposure to DEHP or that... 

Debate is continuing on the safety and toxicity of formaldehyde and its products, especially urea-formaldehyde foam used as insulation in construction and phenol-formaldehyde as a plywood adhesive. Presently the TLV-STEL of formaldehyde is 0.3 ppm. Formaldehyde is on the Reasonably Anticipated to Be Human Carcinogens list. 

U.S. price trends show that cotton and polyester are the most popular for good reason they are the cheapest. Nylon and acrylic have had price increases over the last few years, part of which may be due to improvements and safeguards needed to manufacture their precursors acrylonitrile, butadiene, and benzene, which are on carcinogen lists. 

TCDD was added to the known carcinogen list of the National Toxicology Program. 

Carbon monoxide, 57, 11 Carbonyl compounds, 56, 36 Carboxylic acids, a-bromination of, 55, 31 CARBOXYLIC ACID CHLORIDES, ketones from, 55, 122 CARBYLAMINE REACTION, 55, 96 Carcinogens, list of. 56, 128 58, 168 Carveol, 56, 106 Carveol acetate, 56, 106 Catechols, 58, 125... 

There are three types of carcinogens. List these, and give an example of each. 

NIOSH Carcinogen list. (2002). Available http //www.cdc.gov/niosh/npotocca.html. 

Second, occupational exposures are listed instead of individual chemicals for those cases in which several chemicals may be involved in the exposure and it is not clear which one(s) is responsible for the cancer excesses observed in the workers studied. Third, the listed chemicals and occupational exposures have been demonstrated to be human carcinogens only for the specific groups of individuals upon whom observations were made by epidemiologists whether they increase cancer risk for other individuals exposed under quite different conditions is a separate question, to be treated later in this chapter and in the chapter on risk assessment. Finally, it should be emphasized that there are many additional animal carcinogens listed by IARC and NIH/ NTP that may also pose a carcinogenic risk to humans, but for which sufficient epidemiology data have not been collected keep in mind that a chemical can be demonstrated to be a human carcinogen only if an opportunity exists to study it in exposed humans in a systematic way, and such opportunities are not frequently found. 

What happens to those hydrocarbons, some of them on the carcinogenic list when submitted to sunlight was in 1948 a question raised by Dr. Haagen-Smit that is only now being answered by Dr. Paul Kotin. 

Employees engaged in handling operations involving the carcinogens listed below must be provided with, and required to wear and use, a half-mask filter-type respirator for dusts, mists, and fiimes. A respirator affording higher levels of protection than this respirator may be ... 

Among aldehydes, formaldehyde is a confirmed human carcinogen listed by lARC... 

Carcinogens Listed in the Eieventh Report Part A. Known to be Human Carcinogens. 

Short-term genotoxicity tests, including bacterial and mammalian cell assays, are widely used to assess potential carcinogenicity of chemical and physical agents, owing to the prominent role of genetic effects in the initiation and promotion of cancer however, the predictive value of such tests is far from absolute (114). Of the carcinogens listed as class I substances, Cr(Vl)... 

Carcinogen list (monomer additives) antimony trioxide, cadmium and cadmium ... 

Toxic Release Inventory. Public Data Release. Appendix C. Basis of OSHA Carcinogen Listing for Individual Chemicals. 

Where entry and exit to an area is restricted or controlled because of the existence of any one or more of 13 carcinogens listed at 1926.1103 or 1910.1003, you must post signs with wording, prescribed in those standards. 

Hazard communication, (i) Chemical manufacturers, importers, distributors and employers shall comply with all requirements of the Hazard Communication Standard (HCS) ( 1910.1200) for each carcinogen listed in paragraph (e)(1)(iv) of this section. 

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