Canine tumor cells

Canine tumor cells [28] were from J. Hilton, Johns Hopkins Hospital (Baltimore, MD). 

Previous studies reported that lipid-soluble DAS, DADS, and DATS (100 pM) were more effective in suppressing canine tumor cell proliferation than isomolar water-soluble SAC, S-ethylcysteine, and S-propylcysteine [119]. S-Al-lylmercaptocysteine, one of the more effective water-soluble allyl sulfur compounds, did not reduce the viability of human erythroleukemina cells until concentrations were about 100 pM [123]. While... 

Hogge, G.S., Burkholder, J., Culp, J., Dubielzig, R.R., Albertini, M.R., Keller, E.T. et al. (1998) Development of human granulocyte macrophage-colony stimulating factor transfected tumor cell vaccines for the treatment of spontaneous canine cancer. Hum. Gene Ther., 9, 1851-1861. 

Lymphocytes, platelets, endothelial cells, fibroblast, hepatocytes, astrocytes, intestine, Madin-Darby canine kidney (MDCK) cells, tracheal ciliary epithelia, choroid plexus, eye lens, frog skin, frog urinary bladder, Ehrlich ascites tumor cells Activation of KCI cotransport... 

Garbisa et al., 1980a). Tumor cells have been shown to cross the chorioallantoic membrane, mouse urinary bladder and canine blood vessels in vitro (Poste et al., 1980 Vlaeminck et al., 1972). Verification of active penetration of BM requires a direct interaction of cells with isolated intact BM. 

Basically, harvest of invasive cells after any invasion assay (see Chapter 4) can be used to select a cell population with increased invasive ability. Poste et al. (1980) have used the chorioallantoic membrane (CAM) assay, a canine blood vessel perfusion-invasion chamber, or retrograde injection of tumor cells in the mouse bladder, to select tumor cell variants with respect to their invasive ability. B16-BL6 melanoma cells, widely used as a prototype of highly invasive metastatic cells have been subjected to six rounds of selection with the bladder system. The application of these three systems for selection is described in detail in the original paper (Poste et al., 1980), and will not be treated further here. 

Sundaram SC, Milner JA. Impact of organosulfur compounds in garlic on canine mammary tumor cells in culture. Cancer Lett 1993 74 85-90. 

Sakamoto, K., Reddy, D., Hara, Y., and Milner, J.A., Impact of green or black tea polyphenols on canine mammary tumor cells in culture, Prac. Am. Assoc. Cancer Res., 36, 595, 1995. 

Exocytosis that results in the secretion of 5-hydroxytryptophan and insulin has been monitored from single pancreatic -cells (human, porcine, canine, mouse, and cultured tumor cells), using 9-gm-diameter carbon fiber electrodes [110]. Unmodified electrodes allowed 5-HT quantitation, while modification with a ruthenium ox-ide/cyanoruthenate film allowed selective quantitation of insulin at electrodes positioned 1 pm away from cell surfaces. 

Pavlin D, Cemazar M, Coer A, Sersa G, Pogacnik A, Tozon N (2011) Electrogene therapy with interleukin-12 in canine mast cell tumors. Radiol Oncol 45 31-39... 

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