Cancer impact

Coombs NJ, Taylor R, Wilcken N, Boyages J. HRT and breast cancer impact on population risk and incidence. Eur J Cancer 2005 41(12) 1775-81. 

Koukourakis M, Giatromanolaki A, Kakolyris S, O Byrne KJ, Apostolikas N, Skarlatos J, et al. Different patterns of stromal and cancer cell thymidine phosphorylase reactivity in non-small-cell lung cancer Impact on tumour neoangiogenesis and survival. Br J Cancer 1998 77 1696-1703. 

Osman I, Drobnjak M, Fazzari M, et al. Inactivation of the p53 pathway in prostate cancer impact on tumor progression. Clin Cancer Res. 1999 2082 5. 

EPA has not yet developed a national drinking water standard for DBCP (8), The 1978 DHS drinking water action level of 1.0 ppb was adopted before current information on carcinogenicity was available. EPA has since estimated a lifetime cancer risk from consuming 2 liters per day of water containing 1 part per billion DBCP as 180 excess cancer incidents per million population exposed (9). Figure 7 depicts the EPA estimated cancer risk at various DBCP water concentrations. The State of Hawaii in 1984 adopted a water quality limit of 0.02 ppb (20 ppt)(10). In view of DBCP s potential cancer impacts at very low concentrations, SWRCB has recommended that DHS lower the California DBCP action level to the current detection limit of 0.02 parts per billion (11). 

Luo W, Hershberger PA, Trump DL, Johnson CS (2013) 24-Hydroxylase in cancer impact on vitamin D-based anticancer therapeutics. J Steroid Bioehem Mol Biol 136 252-257... 

Hockel M, Vaupel P (2003) Oxygenation of cervix cancers Impact of clinical and pathological parameters. Adv Exp Med Biol 510 31-35... 

Link KH, Staib L, Kreuser ED, et al (1996) Adjuvant treatment of colon and rectal cancer Impact of chemotherapy, radiotherapy and immunotherapy on routine postsurgical patient management. Recent Res Cancer Res 142 311-352... 

The threshold for toxic injury is not the same for everyone because sensitivity varies greatly among individuals. Most chemicals in consumer products remain untested for health effects, such as cancer, reproductive problems, and the impacts of long-term, low level exposure. How these substances affect women, children, and people with existing conditions is also little studied. Once a person s defenses have been broken down and he or she has become hypersensitive, a wide variety of common chemical exposures can trigger a reaction. Just what products and other chemicals which cause problems varies greatly among affected individuals. 

Latent cancer is calculated to be the primary risk from a nuclear accident (this may be due to the conservatism in the low-dose models). At Chernobyl, most of the deaths were from fire and impact. Chemical process risk depends on the chemicals being processed. Experience shows that processing poisons poses the highest risk to public and workers. 

The recombinant hematopoietic growth factors have had a significant impact on the treatment of cancer, including prevention of serious infections and anemia. 

Tea flavonoids, or tea extracts, have been linked to benefits in reducing the risk of certain cancers and cardiovascular diseases in experimental animals. However, epidemiological studies have produced inconsistent evidence in the relationship between tea drinking and cancer (Blot et a/., 1997 Goldbohm etal, 1996 Hertog eta/., 1997 Yang eta/., 1996). Therefore, further research is needed before definitive conclusions on the impact of tea consumption upon the cancer risk in humans can be reached. The metabolites of catechins and flavonols after consumption of tea infusions have scarcely been investigated, and thus more research is needed as to the role of those compounds in the reported health benefits of tea consumption. 

Bal, D.G. and Foerster, S.B. (1991). Changing the American diet. Impact on cancer prevention policy recommendations and program implications for the American Cancer Society. Cancer 67, 2671-2680. 

Evans, P.H., Campbell, A.K., Yano, E. and Morgan, L.G. (1989a). Environmental cancer, phagocytic oxidant stress and nutritional interactions. In Nutritional Impact of Food Processing (eds. J.C. Somogyi and H.R. Muller) pp. 313-326. Karger, Basel. 

Describe the impact of various oncologic emergencies on the prognosis of patients with cancer. 

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