Canadian Environmental Protection

Health Canada Proposal for Priority Setting for Existing Substances on the Domestic Substances List under the Canadian Environmental Protection Act, 1999 Greatest Potential for Human Exposure. This report describes a proposed priority setting process of existing substances in Canada. A stakeholder meeting was convened to discuss the Complex Exposure Model (comET). 

Boddington, M.J., A.P. Gilman, R.C. Newhook, B.M. Braune, D.J. Hay, and V. Shantora. 1990. Canadian Environmental Protection Act. Priority Substances List Assessment Report No. 1 Polychlorinated Diben-zodioxins and Polychlorinated Dibenzofurans. 56 pp. Available from Commercial Chemicals Branch, Environment Canada, 351 St. Joseph Blvd., Ottawa, Ontario, Canada K1A OH3... 

Canadian Electrolytic Zinc, Ltd., 26 564 Canadian Environmental Protection Act (CEPA), 13 542 23 120-121 Canadian nuclear power program, 17 585 Cancer. See also Breast cancer ... 

Besides, the list also includes the Toxic Substances Control Act in the USA (1976). the Canadian Environmental Protection Act (1994 ), the Chemical Substances Control Law in Japan (1973), and the Australian Chemicals Act (1989). These regulations, which also affect pigments, demand that all new products be registered. Various toxicological test results have to be presented, depending on the country. The discussed legal requirements are supplemented by many other more or less specific environmental acts, not only in the countries thus mentioned, but also in practically all other industrialized nations. 

Environment Canada Health Canada Canadian Environmental Protection Act. Priority substance list assessment report nonylphenol and its ethoxylates. Draft, 2000. 

Armstrong VC, Newhook RC. 1992. Assessing the health risks of priority substances under the Canadian environmental protection act. Regulatory Toxicol Pharmacol 15 111-121. 

Symptoms of exposure Eye contact may cause conjunctival irritation and corneal injury. Extreme irritation to the eyes and nasal passages was observed by male volunteers when exposed to concentrations ranging from 550 to 1,000 ppm (Canadian Environmental Protection Act, 1993). Ingestion of low concentrations may cause nausea and vomiting (Patnaik, 1992). Symptoms of... 

Government of Canada. 1993. Canadian Environmental Protection Act. Priority Substances List Assessment report 3,3 -Diehlorobenzidine. Government of Canada, Health and Welfare Canada, Environment Canada. 

Blaise, C. Sergy, G. Bermingham, N. Van Coillie, R. Biological testing - development, application and trends in Canadian Environmental Protection Lahoratories. Tox. Assess. Int. J. 1988, 3, 385-406. 

CEPA. 1994. Canadian Environmental Protection Act. Priority substances list assessment report ... 

Environment Canada (1997). Environmental Assessments of Priority Substances under the Canadian Environmental Protection Act Guidance Manual Version 1.0. March 1996 EPS/2/CC/3E. Ottawa, ON Environment Canada. 

The Canadian new chemicals program uses two chemical inventories, the Domestic Substances List (DSL) and the Non-Domestic Substances List (NDSL). The DSL includes substances that were, between January 1, 1984, and December 31, 1986, in Canadian commerce, used for manufacturing purposes, or manufactured in or imported into Canada.17 It contains about 23,000 substances. One of the initiatives in the Canadian Environmental Protection Act, 1999 (CEPA, 1999) requires the Minister of the Environment and the Minister of Health to categorize (Section 73, CEPA 1999) and then if necessary, conduct screening assessments (Section 74, CEPA 1999) of substances listed on the DSL to determine whether they are toxic or capable of becoming toxic as defined in the Act. The NDSL is a list of substances not on DSL but in commerce elsewhere in the world.18 The NDSL contains more than 58,000 entries. 

Environment Canada. 2000. Priority substances list assessment report. 2005. Acrolein. Canadian Environmental Protection Act, 1999. Priority substances list assessment report. Environment Canada Health, Canada. 

Meek, M.E., R. Newhook, R.G. Liteplo, and V.C. Armstrong. 1994. Approach to assessment of risk to human health for priority substances under the Canadian Environmental Protection Act. Environ. Carcinogen. Ecotoxicol. Rev. 12(2) 105-134. ... 

The Canadian Environmental Protection Act charges Environment Canada with controlling toxic substances, reducing pollution, and eliminating persistent bioaccumulating toxic substances. Enforcement officers are given the power to issue environmental protection compliance orders on the spot to stop illegal activity and correct any violations of the act. 

The Canadian Environmental Protection Act, 1999 (CEPA 1999) requires the Ministers of the Environment and Health to categorize the substances on the Canadian Domestic Substances List (DSL). The DSL contains 23 000 substances that are subject to categorization (i.e., prioritization). Generally the data selection process involves a search of the scientific literature and databases for quality experimental data for persistence, bioaccumulation potential and inherent toxicity to humans and nonhuman species. If acceptable data are not found, QSARs or other models are used to estimate the persistence, bioaccumulation, and aquatic toxicity of substances based on structure and physical - chemical properties. 

---