Calmodulin mRNA

Vizi S, Gulya K. 2000. Calculation of maximal hybridization capacity (Hmax) for quantitative in situ hybridization a case study for multiple calmodulin mRNAs. J Histochem... 

Matsuoka I, Giulli G, Poyard M, Stengel D, Parma J, Guellaen G, Hanoune J (1992) Localization of adenylyl and gyanylyl cyclase in rat brain by in situ hybridization Comparison with calmodulin mRNA distribution. J. Neurosci., 12. 3350-3360. 

Tschudi, C. and Ullu, E. (1988) Polygene transcripts are precursors to calmodulin mRNAs in trypanosomes. EMBO J. 7 455-463. 

Fig. 4. A The level of calmodulin mRNA in Merit corn root tips that were left in dark (D) or exposed to light (L). Seedlings (48-h-old) were kept either in dark or exposed to light for 40 min. Then the root tips (2 mm) were excised, frozen immediately in liquid K, and used for poly(A) isolation. Two fig of RNA was probed with radiolabeled pPCM-1. The autoradiogram and densitometer scanning results are presented on the lower and upper part of the figure, respectively. B Light-regulated positive gravitropism in Merit corn roots. Corn seedlings (48-h-old) were kept dark (D) or exposed to light for 10 min and left in the dark (L) for 6 h [20]...

Bagni, C., Mannucci, L., Dotti, C. G., and Amaldi, F. (2000). Chemical stimulation of synaptosomes modulates alpha —Ca2+/calmodulin-dependent protein kinase II mRNA association to polysomes. J. Neurosci. 20, RC76. 

Sawamura, Y., Sakagami, H. and Kondo, H., 1996, Localization of mRNA for Ca2+/calmodulin-dependent protein kinase I in the brain of developing and mature rats, Brain Res, 706, pp 259—66. 

Shea, D. K. and Walsh, C. J. (1987) mRNAs for alpha- and beta-tubulin and flagellar calmodulin are among those coordinately regulated when Naegleria gruberi amebae differentiate into flagellates. J. Cell. Biol. 105 1303-1309. 

Several examples of proteins involved in signal transduction pathways are reported to be encoded by auxin-induced mRNAs. These include the 3-subunit of a heterotrimeric G-protein (arcA) [105,106], cyclin-dependent protein kinases (cdc2s) [107-111], and calmodulin (PCM-1 and arCAM) [112,113]. Putative transcription factors are also represented in the list of auxin-induced mRNAs. Auxin-responsive cDNA clones for a G-box binding bZIP transcription factor (SGBF-1) [114] and a homeobox transcription factor (Athb-8) have been reported [115]. Another auxin-responsive mRNA, dbp, was proposed to be a lysine-rich nuclear protein similar to HI histone, and the recombinant protein was shown to bind nonspecilically to DNA [116]. The amino acid sequence of dbp is, however, highly similar (i.e., 67% identity and 80% similarity) to a potato plasma membrane-associated protein called remorin [117]. The remorin protein binds to both simple and complex galacturonides as well as DNA, but is not a nuclear protein in potato... 

Gupta. R. P., Bing, G., Hong, J. S., and Abou-Donia, M. B. (1998). cDNA cloning and sequencing of Ca /calmodulin-dependent protein kinase lla subunit and its mRNA expression in diisopropyl phosphorofluoridate (DFP)-treated hen central nervous system. Mol. Cell. Biochem. 181, 29-39. 

Furuyama, T., Iwahashi,Y.,Tano,Y, Takagi, H., and Inagaki, S (1994) Localization of 63-kDa calmodulin stimulated phosphodiesterase mRNA in the rat brain by in situ hybridization histochemistry. Mol. Brain Res. 26,331-336. 

Key words Pre-mRNA, Poiyadenyiation fector. Tandem affinity purification, Calmodulin binding... 

Chronic stress impairs the hippocampus-dependent spatial memory and blocks LTP in area CAl of the hippocampus possibly by interfering with the function of key signaling molecules involved in memory and LTP including reduction of phosphorylated CaMKII [P-CaMKII], PKCy, and calmodulin and increase in calcineurin levels [Table 47.2 244, 245]. These changes are prevented by chronic nicotine treatment during stress [245]. Another important signaling molecule that is markedly impacted by stress is BDNF. The expression of BDNF mRNA [256-258] and protein levels [245, 259] is decreased after stress. Chronic nicotine treatment restores the protein levels of BDNF in CAl area of the hippocampus of chronically stressed animals [245]. 

---