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Calcium channel blockers monitoring

Calcium channel blockers Monitor for cardiovascular effects similarly to (3 -blockers. If dihydropyridine calcium channel blockers are employed, assess for dependent edema. Consider withdrawal if GERD or constipation responds poorly to therapy. [Pg.510]

CALCIUM CHANNEL BLOCKERS QUINUPRISTIN/ DALFOPRISTIN Plasma levels of nifedipine may be T by qu in upristi n—dalfopristi n Quinupristin inhibits CYP3A4-mediated metabolism of calcium channel blockers Monitor BP closely watch for 1 BP... [Pg.80]

CALCIUM CHANNEL BLOCKERS PRIMIDONE 1 plasma concentrations of calcium channel blockers Primidone induces CYP3A4, which metabolizes calcium channel blockers Monitor PR and BP closely watch for Tbp... [Pg.87]

CALCIUM CHANNEL BLOCKERS ANTIMALARIALS -MEFLOQUINE Risk of bradycardia Additive bradycardic effect mefloquine can cause cardiac conduction disorders, e.g. bradycardia. Also a theoretical risk of Q-T prolongation with co-administration of mefloquine and calcium channel blockers Monitor PR closely... [Pg.88]

NITRATES ANTICANCER AND IMMUNOMODULATING DRUGS- CORTICOSTEROIDS Antihypertensive effects of calcium channel blockers are antagonized by corticosteroids Mineralocorticoids cause sodium and water retention, which antagonizes the hypotensive effects of calcium channel blockers Monitor BP at least weekly until stable... [Pg.132]

BACLOFEN, TIZANIDINE 1. ANAESTHETICS - general 2. ANTICANCER AND IMMUNOMODULATING DRUGS - IL-2 3. ANTIDEPRESSANTS - MAOIs 4. ANTI HYPERTENSIVES AND HEART FAILURE DRUGS 5. ANTI-PSYCHOTICS 6. ANXIOLYTICS AND HYPNOTICS 7. BETA-BLOCKERS 8. CALCIUM CHANNEL BLOCKERS 9. DIURETICS 10. NITRATES 11. PERIPHERAL VASODILATORS-moxisylyte (thymoxamine) 12. POTASSIUM CHANNEL ACTIVATORS t hypotensive effect Additive hypotensive effect. Tizanidine also has a negative chronotropic effect and may cause additive bradycardia with beta-blockers and calcium channel blockers Monitor BP at least weekly until stable. Warn patients to report symptoms of hypotension (light-headedness, dizziness on standing, etc.)... [Pg.489]

BACLOFEN, TIZANIDINE ANAESTHETICS - GENERAL t hypotensive effect Additive hypotensive effect. Tizanidine also has a negative chronotropic effect and may cause additive bradycardia with beta-blockers and calcium channel blockers Monitor BP closely, especially during induction of anaesthesia... [Pg.489]

PROTEASE INHIBITORS CALCIUM CHANNEL BLOCKERS Plasma concentrations of calcium channel blockers are t by protease inhibitors Protease inhibitors inhibit CYP3A4-mediated metabolism of calcium channel blockers Monitor PR, BP and ECG closely 1 dose of calcium channel blocker if necessary (e.g. manufacturers of diltiazem suggest starting at 50% of the standard dose and titrating to effect)... [Pg.625]

Plasma levels of both nifedipine and diltiazem are increased by concurrent use and blood pressure is reduced accordingly. Verapamil is predicted to interact similarly. There are isolated reports of intestinal occlusion attributed to the concurrent use of nifedipine and diltiazem. Note that if nimodipine is used with another calcium-channel blocker, monitoring, with possible dose reduction or discontinuation of the other calcium-channel blocker is recommended. [Pg.865]

Other electrolytes of importance include calcium (especially if the patient is receiving a calcium channel blocker, such as nicardipine) and magnesium, as hypomagnesemia may predispose the patient to seizures, further complicating the ICP management. If the patient received intravenous iodinated contrast as part of their stroke evaluation, then careful monitoring of the blood urea nitrogen (BUN) and creatinine levels is necessary to detect contrast nephropathy. [Pg.166]

Hypertension Calcium channel blockers ACE inhibitors ARBs Diltiazem, verapamil inhibit CSA/TAC metabolism Dihydropyridines may potentiate CSA-gingival hyperplasia May exacerbate hyperkalemia monitor K+, SCr to assess for renal allograft vascular disease may be useful in posttranplant erythrocytosis (hematocrit greater than 55%)... [Pg.847]

FIGURE 6-2. Algorithm for the treatment of acute (top portion) paroxysmal supraventricular tachycardia and chronic prevention of recurrences (bottom portion). Note For empiric bridge therapy prior to radiofrequency ablation procedures, calcium channel blockers (or other atrioventricular [AV] nodal blockers) should not be used if the patient has AV reentry with an accessory pathway. (AAD, antiarrhythmic drugs AF, atrial fibrillation AP, accessory pathway AVN, atrioventricular nodal AVNRT, atrioventricular nodal reentrant tachycardia AVRT, atrioventricular reentrant tachycardia DCC, direct-current cardioversion ECG, electrocardiographic monitoring EPS, electrophysiologic studies PRN, as needed VT, ventricular tachycardia.)... [Pg.83]

The adverse effects of atazanavir include fever, jaundice/scleral icterus, myalgia and diarrhea. Its coadministration is not recommended with the drugs that induce cytochrome P-450 isoenzyme CYP3A4. Ritonavir increases plasma concentrations of atazanavir. It is an inhibitor of isoenzymes CYP3A4, CYP2C8 and UGT1A1. The coadministration of atazanavir with calcium channel blockers, HMG-CoA reductase inhibitors, immunosuppressants and phosphodiesterase 5 inhibitors should be carefully monitored. [Pg.192]

Calcium channel blockers and prostaglandins have been used to reduce the nephrotoxic effects of cyclosporin during kidney transplantation.201 Interleukin-2 should be taken cautiously when coadministered with NSAIDs.202 Coadministration of tamoxifen with allopurinol and anticoagulants should be monitored carefully.203... [Pg.360]

AMIODARONE CALCIUM CHANNEL BLOCKERS Risk of bradycardia, AV block and 1 BP when amiodarone coadministered with diltiazem or verapamil Additive negative inotropic and chronotropic effect. Also, amiodarone inhibits intestinal P-gp, which t the bioavailability of diltiazem and verapamil Monitor PR, BP and ECG closely watch for heart failure... [Pg.12]

AMIODARONE POTASSIUM-SPARING DIURETICS Risk of T levels of eplerenone with amiodarone risk of hyperkalaemia directly related to serum levels Calcium channel blockers inhibit CYP3A4-mediated metabolism of eplerenone Restrict dose of eplerenone to 25mg/day. Monitor serum potassium concentrations closely watch for hyperkalaemia... [Pg.13]

MORACIZINE CALCIUM CHANNEL BLOCKERS Co-administration is associated with t bioavailability of moracizine and 1 availability of diltiazem Postulated that diltiazem inhibits metabolism of moracizine, while moracizine t metabolism of diltiazem the precise mechanism of interaction is uncertain at present Monitor PR, BP and ECG adjust doses of each drug accordingly... [Pg.25]

ANTI HYPERTENSIVES AND HEART FAILURE DRUGS CALCIUM CHANNEL BLOCKERS T hypotensive effect Additive hypotensive effect may be used therapeutically Monitor BP at least weekly until stable. Warn patients to report symptoms of hypotension (light-headedness, dizziness on standing, etc.)... [Pg.47]

ASPIRIN CALCIUM CHANNEL BLOCKERS 1 antihypertensive effect with aspirin effect not noted with low-dose aspirin Aspirin may cause sodium retention and vasoconstriction at possibly both renal and endothelial sites Monitor BP at feast weekly until stable when high-dose is aspirin prescribed... [Pg.57]

CALCIUM CHANNEL BLOCKERS ALCOHOL 1. Acute alcohol ingestion may t hypotensive effect. Chronic moderate/heavy drinking 1 hypotensive effect 2. Verapamil may t peak serum concentration and prolong the effects of alcohol 1. Additive hypotensive effect with acute alcohol excess. Chronic alcohol excess is associated with hypertension 2. Uncertain at present, but presumed to be due to an inhibition of hepatic metabolism of alcohol 1. Monitor BP closely as unpredictable responses can occur. Advise patients to drink only in moderation and avoid large variations in the amount of alcohol drunk 2. Warn the patient about the potentiation of the effects of alcohol, particularly the risks of driving... [Pg.78]

CALCIUM CHANNEL BLOCKERS ANAESTHETICS -GENERAL, INHALATIONAL t hypotensive effects of dihydropyridines, and hypotensive/bradycardic effects of diltiazem and verapamil Additive hypotensive and negative inotropic effects. General anaesthetics tend to be myocardial depressants and vasodilators they also 1 sinus automaticity and AV conduction Monitor BP and ECG closely... [Pg.78]

CALCIUM CHANNEL BLOCKERS ANAESTHETICS - LOCAL Case reports of severe 1 BP when bupivacaine epidural was administered to patients on calcium channel blockers Additive hypotensive effect both bupivacaine and calcium channel blockers are cardiodepressant in addition, epidural anaesthesia causes sympathetic block in the lower limbs, which leads to vasodilatation and 1 BP Monitor BP closely. Preload intravenous fluids prior to the epidural... [Pg.78]

See other pages where Calcium channel blockers monitoring is mentioned: [Pg.1269]    [Pg.1269]    [Pg.504]    [Pg.71]    [Pg.371]    [Pg.503]    [Pg.211]    [Pg.437]    [Pg.1]    [Pg.640]    [Pg.656]    [Pg.70]   
See also in sourсe #XX -- [ Pg.140 ]



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