Bristol University

For example, each subunit of the dimeric glycolytic enzyme triosephos-phate isomerase (see Figure 4.1a) consists of one such barrel domain. The polypeptide chain has 248 residues in which the first p strand of the barrel starts at residue 6 and the last a helix of the barrel ends at residue 246. In contrast, the subunit of the glycolytic enzyme pyruvate kinase (Figure 4.5), which was solved at 2.6 A resolution in the laboratory of Ffilary Muirhead, Bristol University, UK, is folded into four different domains. The polypeptide chain of this cat muscle enzyme has 530 residues. In Figure 4.5, residues 1-42... 

The stmcture was determined to 2.8 A resolution in the laboratory of Tom Steitz, Yale University, (d) The glycolytic enzyme phospho-glycerate mutase, which catalyzes transfer of a phos-phoryl group from carbon 3 to carbon 2 In phosphoglycerate. The structure was determined to 2.S A resolution in the laboratory of Herman Watson, Bristol University, UK. (Adapted from J. Richardson.)... 

One of the Department s luminaries, Ronald Ottewill, went off to Bristol University, where he became first professor of colloid science and then professor of physical chemistry, both in the Department of Physical Chemistry. The Bristol department has been one of the most distinguished exponents of colloid science in recent years, but Ottewill considers that it is best practised under the umbrella of physical chemistry. 

Born in London, Paul May grew up in Redditch, Worcestershire. He went on to study at Bristol University, where he graduated with a first class honours in chemistry in 1985. He then joined GEC Hirst Research Centre in Wembley where he worked on semiconductor processing for three years, before returning to Bristol to study for a PhD in plasma etching of semiconductors. His PhD was awarded in 1991, and he then remained at Bristol to co-found the CVD diamond research group. In 1992 he was awarded a Ramsay Memorial Fellowship to continue the diamond work, and after that a Royal Society University Fellowship. In October 1999 he became a full-time lecturer in the School of Chemistry at Bristol. He is currently 36 years old. His scientific interests include diamond films, plasma chemistry, interstellar space dust, the internet and web technology. His recreational interests include table-tennis, science fiction, and heavy metal music. 

F.G.A. Stone Yes, I would expect cleavage of the W=C bond in [(n-C5H5)(0C)2W=CR] to occur in certain reactions. Indeed, we believe we have observed C=W bond cleavage in a reaction of the tungsten compound with a carbido(carbonyl)iron cluster. Interestingly, [(n-C5H5)(0C)2W=CR] reacts with sulphur to yield [(n-C5H5)(0C) W S CR S] (I. Moore, Bristol University). 

Department of Physiology University of Bristol University Walk Bristol BS8 1TD UK... 

Lidiard, A. B., Report on the Conference on Defects in Crystalline Solids held at Bristol University in July, 1954, p. 283, Physical Society, London, 1955. 

S. Lam, Ph.D. thesis, Bristol University, 1994. (We gratefully acknowledge the help rendered by Dr P. Sperry of Rohm and Haas and Prof. W.B. Russel of Princeton University during this work.)... 

Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Department of Clinical Science at South Bristol, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BSl 3NY, UK Astrid.Linthorst bristol.ac.uk... 

FIGURE 3.10 (a) Chemical-vapour deposition reactor (b) cross section of a 100 pm-thick CVD diamond film grown by DC arc jet. The columnar nature of the growth is evident, as is the increase in film quality and grain size with growth time. (Courtesy of Dr. Paul May and Prof. Mike Ashfold, Bristol University.)... 

FIGURE 11.1 SEM images of (a) a diamond film grown with methane, hydrogen, and 0.2% PH3, showing (100) square facets and (b) a diamond film grown at lower substrate temperature—now the crystals are predominantly (7 iij triangular facetted. (Courtesy of Dr. P.D. May and Professor M.N.R.Ashfold, Bristol University.)... 

The first report, received on February 25, by Varinder Aggarwal of Bristol University (Organic Lett. 2004, 6, 1469) is representative of all three. Ohira homologation of the aldehyde 6 gave the enyne... 

The following organisations are thanked for their kind donation of samples Institute Francais du Petrole, British Petroleum, Norsk Hydro. We are grateful to the analytical departments at Bristol University and at BP Research Centre for the elemental analyses. Dr. A. Pepper (BP) is acknowledged for provision of burial history information for the Monterey Fm. kerogens. ll Buxton (Geolab Nor) is thanked for selected TOC determinations. Dr. J.M. Jones (University of Newcastle) is thanked for vitrinite reflectance analyses. We thank Dr. A.K. Burnham for supplementary kinetic analyses. W. Pool is thanked for technical assistance. Drs. K. Peters, W.L. Orr and C.M. White are thanked for critical reviews. 

The study of ferroelectrics has been greatly assisted by so-called phenomenological theories which use thermodynamic principles to describe observed behaviour in terms of changes in free-energy functions with temperature. Such theories have nothing to say about mechanisms but they provide an invaluable framework around which mechanistic theories can be constructed. A.F. Devonshire was responsible for much of this development between 1949 and 1954 at Bristol University. 

In 1945, Ken, who was now Lecturer at Bristol University, was again invited by Hirst to move with him to Manchester University, this time as Senior Lecturer in Organic Chemistry. Once more, it became necessary for Hirst to concentrate his efforts on University and Government committee work. Ken Jones, therefore, took charge of the carbohydrate-research group, and supervised the completion of the explosives work. During this interval, Ken enjoyed the able collaboration of Dr. T. G. Halsall in studies on the structures of starch, cellulose, and glycogen, and on the oxidation of carbohydrates by periodate. The close association of Ken with Professor Hirst, which continued at Manchester University until 1948, was a tremendously fruitful one over 50 joint publications resulted from their research on complex polysaccharides. 

In 1948, Edmund Hirst moved to Edinburgh University, and Ken returned to Bristol University as Reader in Organic Chemistry. At Bristol, Ken rapidly developed his own carbohydrate-research group and, with great foresight, impressed upon his colleagues the need to apply biochemical methods to the study of natural products, a point of view fully shared by his brilliant assistant (later Professor) Leslie Hough. 

Department of Biochemistry, Medical School, University of Bristol, University Walk, Bristol BS81TD, England... 

Pease, M. F. (23 February 1942). Some Reminiscences of University College, Bristol. Bristol University Archives. 

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