Bone morphogenetic protein

Bone morphogenetic proteins (BMPs) A family (eight or more) of secreted proteins with a variety of actions on bone many induce ectopic bone growth. 

Hu J, Sebald W (2011) N-terminal specificity of PEGylation of human bone morphogenetic protein-2 at acidic pH. Int J Pharm 413 140-146... 

Reynolds, A.M., Xia, W., Holmes, M.D., Hodge, S.J., Danilov, S., Curiel, D.T., Morrell, N.W., and Reynolds, P.N. (2007) Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension. Am. J. Physiol. Lung Cell Mol. Physiol. 292, L1182-L1192. 

Bone morphogenetic proteins stimulate astrogenesis 508 Neural crest stem cells give rise to neuronal or glial derivatives in the peripheral nervous system 509... 

Mehler, M., Mabie, P., Zhu, G., Gokhan, S. and Kessler, J. Developmental changes in progenitor cell responsiveness to bone morphogenetic proteins differentially modulate progressive CNS lineages. Dev. Neurosci 22 74-85, 2000. 

Gross, R. E., Mehler, M. F., Mabie, P. C., Santschi, L., Ngo, P. and Kessler, J. A. Promotion of astroglial lineage commitment from mammalian subventricular zone progenitor cells by bone morphogenetic proteins. Neuron 17 1-20,1996. 

Schneider, C., Wicht, H., Enderich, J., Wegner, M. and Rohrer. H. Bone morphogenetic proteins are required in vivo for the generation of sympathetic neurons. Neuron. 24 861-870,1999. 

Canalis E, Economides AN, Gazzerro E (2003) Bone morphogenetic proteins, their antagonist, and the skeleton. Endocr Rev 24 218-235... 

Rickard DJ, Hofbauer LC, Bonde SK, Gori F, Spelsberg TC, Riggs BL (1998) Bone morphogenetic protein-6 production in human osteoblastic cell lines. Selective regulation by estrogen. J Clin Invest 101 413-422... 

Hofbauer LC, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S (1998) Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines. BioChem Biophys Res Commun 250 776-781... 

CUB Domain first found in Clr, Cls, uEGF, and bone morphogenetic protein E(M) 0(0) 57(95) 1SFP... 

Xu et al. [76] have showed that human embryonic stem cells by treatment with bone morphogenetic protein-4 can be driven to differentiate into tro-phoblasts which have the ability to syncytialize and form confluent mono-layers. The differentiated cells express a number of trophoblast markers and secrete placental hormones and thus may provide an alternative placental model. Under the culture conditions used, however, the cells propagated poorly. 

Yim, K., Abrams, J., and Hsu, A. (1995). Gapillary zone electrophoretic resolution of recombinant human bone morphogenetic protein-2 glycoforms — an investigation into the separation mechanisms for an exquisite separation. /. Chromatogr. A 716, 401—412. 

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