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Bone morphogenetic proteins BMPs

Bone morphogenetic proteins (BMPs) A family (eight or more) of secreted proteins with a variety of actions on bone many induce ectopic bone growth. [Pg.548]

Fig. 6.5 Signalling through SMAD proteins. Receptor complexes, formed with transforming growth factor.p (TGF-p) and related factors, activins, and bone morphogenetic proteins (BMPs), consist of two serine/threonine receptor kinases, the type II and type I receptors. Binding of the ligand results In autophosphorylation of type I receptors. The activated type I receptors in turn phosphoryiate and activate R-SMADs SMADs 1,... Fig. 6.5 Signalling through SMAD proteins. Receptor complexes, formed with transforming growth factor.p (TGF-p) and related factors, activins, and bone morphogenetic proteins (BMPs), consist of two serine/threonine receptor kinases, the type II and type I receptors. Binding of the ligand results In autophosphorylation of type I receptors. The activated type I receptors in turn phosphoryiate and activate R-SMADs SMADs 1,...
Three major families of growth factors, namely, bone morphogenetic proteins (BMPs), members of transforming growth factor P-family, the Wnt family, as well as the fibroblast growth factor family, play an important role in cardiogenesis [101]. [Pg.66]

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See also in sourсe #XX -- [ Pg.102 , Pg.103 , Pg.103 , Pg.104 ]

See also in sourсe #XX -- [ Pg.414 , Pg.525 ]

See also in sourсe #XX -- [ Pg.127 , Pg.164 ]



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