Biomedical luminescence

Special issues of the International Symposia on Quantitative Luminescence Spectrometry in Biomedical Sciences. Anal Chim Acta 290 1-248, 1994 and Anal Chim Acta 303 1-148, 1995. 

The goal of luminescent sensing is perhaps to implement methods and instrumentation capable of performing simple, accurate, and precise measurements in real time. These qualities of sensing systems are especially desirable in the biomedical field in which relevant physiological parameters may change constantly during time expands from a fraction of a second to several hours. 

W. R. G. Baeyens, D. De Keukelaire, and K. Korkidis (Eds.), Luminescence Techniques in Chemical and Biomedical Analysis, Marcel Dekker, New York (1991). 

DeJong G, Kwakman P. Chemi-luminescence detection for high-performance liquid-chromatography of biomedical samples. Journal of Chromatography. Biomedical Applications 492, 319-343, 1989. 

Faulkner, S. Matthews, J. L. Fluorescent and Luminescent Complexes for Biomedical Applications, Comprehensive Coordination Chemistry II , Vol. 9 Eds. McCleverty, J. Meyer, T. J. Pergamon, 2003, p. in press, in press. 

In contrast to polymers, the structural precision and hence more uniform properties of dendrimers predestine them primarily for applications in the biomedical sector. A further reason for interest in these compounds is that effects such as luminescence can be enhanced by straightforward substitution and high local concentrations of certain structural elements and functionalities can be obtained. 

Applications of fiber-optic pH sensors in environmental analysis, biomedical research, medical monitoring, and industrial process control have been reviewed by Lin [67]. A multitude of luminescent systems for pH monitoring are commercially available, mostly under special trademarks. Pyrene [68-70], coumarin, bromothymol blue [71] and fluorescein [72-74] derivatives are typical examples that have been used in research in the past two decades. Carboxyfluorescein derivatives have been directly applied to skin tissue samples for the lifetime imaging of pH gradients in the extracellular matrix of the epidermis [75]. Two-photon excitation microscopy became an estab-... 

Takuya Nishioka, Koichi Fukui and Kazuko Matsumoto, Lanthanide chelates as luminescent labels in biomedical analyses 171... 

LANTHANIDE CHELATES AS LUMINESCENT LABELS IN BIOMEDICAL ANALYSES... 

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