Biomaterials clinical applications

T. Yamamuro, T. Nakamura, H. lida, K. Kawanabe, Y. Matsuda, K. Ido, J. Tamura, Y. Seneba, Development of bioactive bone cement and its clinical applications. Biomaterials 19 (1998) 1479-1482. 

A variety of researches on bio-conjugate (or bio-mimicking) materials have been carried out during the last few years. As seen in Table 1, the aims and scope of many of the researchers are directly connected with clinical applications. For instance, endothelial-cell seeding (or sodding) on the luminal surface of vascular grafts is a widely-known technique [165-169] for improving the blood compatibility of polymetric materials. On the other hand, not a few of researchers are oriented to the exploitation of future possibilities of biomaterials. 

Boretos JW, Eden M (1984) Contemporary biomaterials, material and host response, clinical applications, new technology and legal aspects. Noyes Publications, Park Ridge, NJ... 

It is of prime importance to establish the assessment method relevant to the expected clinical application of biomaterials when they are to be studied for improvement of the surface blood compatibility. A large hurdle preventing... 

Biomaterials are used in diverse clinical applications. Table 1 lists several examples of applications of biomaterials in medicine. Note that metals, ceramics. 

Elisseeff, J.H. Langer, R. Yamada, Y. Biomaterials for tissue engineering. In Tissue Engineering and Biodegradable Equivalents Scientific and Clinical Applications Lewandrowski, K.-U., Wise, D., Trantolo, D., Gresser, J.D., Yaszemski, M.J., Altobelli, D.E., Eds. Marcel Dekker New York, 2002 1-24. 

Journal of Biomaterials Applications. London Sage Publications. ISSN 0885-3282. Articles emphasize development, manufacture and clinical applications, and compatibility of biomaterials. Peer-reviewed. 

Journal of Biomedical Materials Research Part B Applied Biomaterials. Hoboken, NJ Wiley Interscience. ISSN 0021-9304. A section of the Journal of Biomedical Materials Research, Applied Biomaterials reports on device development, implant retrieval and analysis, manufacturing, regulation of devices, liability and legal issues standards, reviews of different device areas, and clinical applications relating to applied biomaterials. Peer-reviewed. Official publication of the Society for Biomaterials (US) and Japanese Society for Biomaterials, the Australian Society for Biomaterials, and the Korean Society for Biomaterials. 

Among the many classes of polymeric materials now available for use as biomaterials, non-degradable, hydrophobic polymers are the most widely used. Silicone, polyethylene, polyurethanes, PMMA, and EVAc account for the majority of polymeric materials currently used in clinical applications. Consider, for example, the medical applications listed in Table A.l most of these applications require a polymer that does not change substantially during the period of use. This chapter describes some of the most commonly used non-degradable polymers that are used as biomaterials, with an emphasis on their use in drug delivery systems. 

Biomaterials play an important role in a variety of clinical applications in wound healing, regeneration, and tissue engineering. Important features of such materials include the... 

A. Pizzoferrato, P G. Machetti, and A. Ravaglioli, Biomaterials and Clinical Applications, Elsevier, Amsterdam, 1987. 

K5rriacos, A. A. et al.. Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers. Biomaterials, 17, 93, 1996. 

A comprehensive definition of a biomaterial was provided at the National Institutes of Health (NIH) Consensus Development Conference on the Clinical Applications of Biomaterials in the United States ... 

Galletti, P.M. and Boretos, J.W. (1983) Report on the Consensus Development Conference on Clinical Applications of Biomaterials J. Biomed. Mat. Res. 17, 539. Defined biomaterial. ... 

Abstract This chapter focuses on dental biomaterials designed for permanent placement in the mouth. The development of flowahle polymer-ceramic composites is traced and their rheological properties, such as pseudoplasticity and thixotropy, discussed. Also considered are some materials that are being developed for root canal therapy, including calcium phosphate cements. There is vast scope for research into materials development, clinical applications and fundamental mechanisms. 

Nakamura, T., Hitomi, S., Shimamoto, T. et al. (1987) Surgical application of biodegradable films prepared from lactide and E-caprolactone, in Biomaterials and Clinical Applications (eds A. Pizzoferrato, P.G. Marchetti, A. RavagUoli and A.J.C. Lee), Elsevier Science Publishers B.V., Amsterdam (The Netherlands), pp. 759-764. 

S. Nagaoka and A. Nakao. Clinical application of antithrombogenic hydrogel with long poly(ethylene oxide) chains. Biomaterials 11 119-121 (1990). 

The topics outlined in this Handbook may be used as a resource in imder-graduate, as well as graduate, courses in biomaterials and orthopedic biomechanics. Students in these disciplines can learn a great deal from exposure to the historical development of total joint replacements within the context of UHMWPE. The first two main sections of this book, which cover tire fimda-mentals of UHMWPE and clinical applications in the spine and upper and lower extrenrities, are intended as a resource for imdergraduate instruction. 

Pavek, V., Novak, Z., Stmad, Z Kudmova, D., and Navratilova, B. (1994), Clinical application of bioactive glass-ceramic BAS-0 for filling cyst cavities in stomatology. Biomaterials 15(5) 353-358. 

Talja, M., Valimaa, T., Tammela, T., Petas, A., and Tormala, P. (1997) Bioab-sorbable and biodegradable stents in urology. /. Endourol, 11 (6), 391-397. Athanasiou, K.A., Niederauer, G.G., and Agrawal, C.M. (1996) Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers. Biomaterials, 17 (2), 93-102. 

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