Biologically active constituents

Interest in chemical variation in Phytolacca dodecandra L Hert. stems from its potentially important biologically active constituents, perhaps the most significant of which is the mollnscicidal componnd lemmatoxin. Attempts to measure variation within this taxon, which occnrs widely on the African continent, have involved a stndy of morphological featnres (Adams et al., 1989) and the comparative chemical work to be described here (Adams et al., 1990). This more recent study involved analysis of nonpolar constitnents from three populations from Ethiopia, and one... 

Before the discovery of specific cannabinoid receptors, the term cannabinoid was used to describe the biologically active constituents of the Cannabis sativa plant, including A -THC (67), cannabidiol (68) and their analogues and derivatives, many of which have characteristic pharmacological effects. 

Hamburger MO, Cordell GA, Ruangrungsi N. Traditional Medicinal Plants of Thailand XVn. Biologically Active Constituents of Plumeria rubra. Journal of Ethnophar-macology 1991 33(3) 289-292. 

Several types of bioactive compounds have been reported from the genus Broussonetia including glycosidase inhibitory alkaloids and aromatase inhibitory or cytotoxic flavonoids. This chapter reviews the biologically active constituents from the genus Broussonetia reported by the end of 2001. 

The stmcture of silybin (1), C25H22O10, mp 158-160°C, [aJo +12.6°cm g the principal biologically active constituent of S. marianum, was first settled by Pelter... 

Delta-9-Tetrahydrocannabinol (Delta-9-THC) and, to a small extent, also Delta-8-THC are the biologically active constituents in extracts of the plant Cannabis sativa (marihuana, hashish) and are responsible for the effects on the human central nervous system (CNS). Potential historical and contemporary therapeutic uses of cannahis preparations include, interalia, analgesia, emesis, anorexia, glaucoma and motor disorders. 

T Tsuruga, Y Ebizuka, J Nakajima, YT Chun, H Noguchi, Y litaka, U Sankawa. Biologically active constituents of Magnolia salicifolia Inhibitors of induced histamin release from rat mast cells. Chem Pharm Bull 39 3265-3271, 1991. 

To date more than 100 species from the large genus Baccharis have been investigated chemically. The most widespread compounds are clerodane diterpene derivatives, but labdane derivatives have also been isolated. Furthermore, typical acetylenic compounds, baccharis oxide, a unique triterpene, and derivatives of hydroxyacetophenone are present, although it is mainly other biologically active constituents, e.g. flavonoids, sesquiterpenes and essential oils that have been reported in the last years. The constituents of Baccharis species compiled from different sources are presented below. 

China and Japan. The biologically active constituents are considered to be a series of saponin glycosides known as ginsenosides, panaxosides or pen tuyui fins Review of constituents J, P. Hov, Comp, Med. East West 5, 123-145 (197 ). Isoln and identification of ginseng saponin glycosides S. 

Two major enzyme inhibition assays, targeting for HMG-CoA reductase and squalene synthase, respectively, have led to the isolation and synthesis of a variety of therapeutic agents and biologically active constituents as potent inhibitors of cholesterol biosynthesis. 

Two compounds most likely derived from the same biogenetic pathway as hyperforin 10, hyperevolutin A 19 and B 20 were isolated from an African species, Hypericum revolutum VAHL, by Decosterd et al. [50]. A petroleum ether extract of the root bark of this plant yielded both components as the main biologically active constituents. The structure of... 

Mehta (Eds), Biology and Chemistry of Plant Trichomes. The Chemistry of Biologically Active Constituents Secreted and Stored in Plant Glandular Trichomes, Plenum Press, 1984, pp. 187-242. 

A preliminary chromatographic analysis of phytochemical constituents of selected species the three subfamilies in the Dipterocarpaceae was reported in 1977 [5], and indicated the presence of triterpenoids similar to dipterocarpol as constituents common to the three subfamilies. It was recommended that further studies on phenolic compounds such as flavonoids, which might be used as chemotaxonomic markers, should be carried out [5]. The present chapter focuses on the biologically active constituents of the plants in the family Dipterocarpaceae. 

Table 1. Biologically Active Constituents of Plants in the Snbfamily Dipterocarpoideae...

McNaughton SA, Marks GC (2003) Development of a food composition database for the estimation of dietary intakes of glucosinolate, the biologically active constituents of cruciferous vegetables. Br J Nutr 3 687-697... 

Popova, M., Bankova, V., Butovska, D., Petkov, V., Damynova, BN., Sabatini, AG., Marcazzan, GL Bogdanov, S (2004). Validated methods for the quantifications of biologically active constituents of poplar-type propolis. Phytochemical Analysis, Vol. 15, pp.235-240. ISSN 1099-1565... 

Kelsey, R. L., G. W. Reynolds, and E. Rodriguez, The chemistry of biologically active constituents secreted and stored in plant glandular trichomes, in Biology and Chemistry of Plant Tri-chomes (E. Rodriguez, P. L. Healey, and I. Mehta, eds.), 187-241, Plenum Press, New York, 1984. 

Inamdar PK, Teola RD, Ghogare AB, de Souza NJ (1996) Determination of biologically active constituents in Centella asiatica. J Chromalogr A 742 127—130... 

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