Bioinformatics target discovery

Eagan R, Swindells M. Bioinformatics, target discovery and the pharmaceutical/ biotechnology industry. Curr Opin Mol Ther 2000 2(6) 655 - 661. 

Chapter 18—BioIT Architecture Software Architecture for Bioinformatics Research Dickson explains the variety of requirements that the research process imposes on any BioIT architecture used in target identification and validation. He focuses on the types of components (e.g., architecture, environment, and services) that are necessary to support the target discovery process. 

Each of these ontologies offers the same opportunity to provide benefit to the life sciences industry. It is easily seen that even this small, unrepresentative set of ontologies covers many major areas of interest in target discovery anatomy, tissue, pathways, proteins, and chemicals. Bioinformatics resources are at the point where much of the knowledge they hold might be open to computational processes across organizations. 

The Impact of Genomics, Systems Biology, and Bioinformatics on Drug and Target Discovery Challenge and Opportunity... 

Finding Targets for Therapeutic Intervention Bioinformatics and Vaccine Discovery Challenges... 

II. Product Summary Jubilant Biosys has created some content products in the bioinformatics and chemoinformatics area. These products leverage Jubilant s curation services to incorporate extensive curated databases with structured query modules and front-ends for data retrieval. The content is for the drug discovery process, specifically in the areas of target prioritization and lead identification. The databases are available in Oracle, SD format, and ISIS/Base DB formats and can be exported. The database can be queried across text, structure, substructure and sequences with built-in query modules. Some of the key parameters on which information is curated are ... 

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