Bioinformatics industrialization

We have been developing cutting-edge data analysis tools for the pharmaceutical industry for over a decade, with a particular focus in the fields of cheminformatics and bioinformatics. We now describe how our insights apply to these areas. 

Within the pharmaceutical industry we have progressed from the point where computers in the laboratory were rarely present or used beyond spreadsheet calculations. Now computers are ubiquitous in pharmaceutical research and development laboratories, and nearly everyone has at least one used in some way to aid in his or her role. It should come as no surprise that the development of hardware and software over the last 30 years has expanded the scope of computer use to virtually all stages of pharmaceutical research and development (data analysis, data capture, monitoring and decision making). Although there are many excellent books published that are focused on in-depth discussions of computer-aided drug design, bioinformatics, or other related individual topics, none has addressed this broader utilization of... 

KiyotakaY. Hara Consolidated Research Institute for Advanced Science and Medical Science and Medical Care, Waseda University, Tokyo, Japan Atsunori Hiratsuka Research Center of Advanced Bionics, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan Setsuo Hirohashi Proteome Bioinformatics Project, National Cancer Center Research Institute, Tokyo, Japan... 

For these reasons, our research group includes basic researchers including a bioinformatics specialist, clinicians, pathologists, and industry partners, in a way that best-optimizes the use of 2D-DIGE related methods for biomarker development studies (Fig. 4). 

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