Beta-arrestin

Lefkowitz RJ, Shenoy SK (2005) Transduction of receptor signals by beta-arrestins. Science 308 512-517... [Pg.49]

Reiter E, Lefkowitz RJ (2006) GRKs and beta-arrestins roles in receptor silencing, trafficking and signaling. Trends Endocrinol Metab 17 159-165... [Pg.1207]

Bleich A, Gelkopf M, Weizman T, et al Benzodiazepine abuse in a methadone maintenance treatment clinic in Israel characteristics and a pharmacotherapeutic approach. Isr J Psychiatry Relat Sci 39 104-112, 2002 Bohn LM, Gainetdinov RR, Lin FT, et al Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Nature 408 720— 723, 2000... [Pg.96]

Cheng ZJ, Zhao J, Sun Y, Hu W, Wu YL, Cen B, Wu GX, Pei G (2000) Beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4. J Biol Chem 275 2479-2485... [Pg.241]

Huttenrauch F, Nitzki A, Lin FT, Honing S, Oppermann M (2002) Beta-arrestin binding to CC chemokine receptor 5 requires multiple C-terminal receptor phosphorylation sites and involves a conserved Asp-Arg-Tyr sequence motif. J Biol Chem 277 30769-30777 Imitola J, Raddassi K, Park KI, Mueller FJ, Nieto M, Teng YD, Frenkel D, Li J, Sidman RL, Walsh CA, Snyder EY, Khoury SJ (2004) Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor lalpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci U S A 101 18117-18122... [Pg.244]

McDonald PH, Chow CW, MiUer WE, Laporte SA, Field ME, Lin FT, Davis RJ, Lefkowitz RJ (2000) Beta-arrestin 2 a receptor-regulated MAPK scaffold for the activation of JNK3. Science 290 1574-1577... [Pg.394]

KohoutTA, Nicholas SL, Perry SJ, Reinhart G, Junger S, Struthers RS. Differential desensitization, receptor phosphorylation, beta-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7. J Biol Chem 2004 279(22) 23214-23222. [Pg.49]

Galliera E, Jala VR, Trent JO, et al. beta-Arrestin-dependent constitutive internalization of the human chemokine decoy receptor D6. J Biol Chem 2004 279(24) 25590-25597. [Pg.52]

Barlic J, Andrews JD, Kelvin AA, et al. Regulation of tyrosine kinase activation and granule release through beta-arrestin by CXCRI. Nat Immunol 2000 1(3) 227-233. [Pg.52]

Barlic J, Khandaker MH, Mahon E, et al. Beta-arrestins regulate interleukin-8-induced CXCRI internalization. J Biol Chem 1999 274(23) 16287-16294. [Pg.52]

Agonist-dependent desensitization of the kappa opioid receptor by G protein receptor kinase and beta-arrestin. J Biol Chem 1999 274 233802-233807. [Pg.486]

Bohn L, Lefkowitz R et al. Enhanced morphine analgesia in mice lacking beta-arrestin 2. Science 1999 286 2495-2498. [Pg.487]

Luttrell, L. M. and Lefkowitz, R. I. The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. /. Cell Sci. 115 455-465, 2002. [Pg.224]

Shenoy, S. K., et al.. Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science, 2001,... [Pg.99]

Bohn LM, Gainetdinov RR, Sotnikova TD, Medvedev lO, Lefkowitz RJ, et al. 2003. Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knockout mice. J Neurosci 23(32) 10265-10273. [Pg.243]

Ferguson, S. S., Downey, W. E. 3., Colapietro, A. M., Barak, L. S., Menard, L., and Caron, M. G. (1996) Role of beta-arrestin in mediating agonist-promoted G protein-conpled receptor internalization. Science. 271, 363-366. [Pg.105]

Lefkowitz, R. J. (1998) G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization. J. Biol. Chem. 273, 18677-18680. [Pg.106]

DeWire SM, et al Beta-arrestins and cell signaling. Annu Rev Physiol 2007 69 483. [PMID 17305471]... [Pg.56]

Krupnick JG, Benovic JL (1998) The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol 38 289-319 Lefkowitz RJ (1998) G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization. J Biol Chem 273(30) 18677-18680 Lefkowitz RJ (2004) Historical review a brief history and personal retrospective of seven-trans-membrane receptors. Trends Pharmacol Sci 25(8) 413—422 Liang BT, Jacobson KA (1998) A physiological role of the adenosine A3 receptor sustained car-dioprotection. Proc Natl Acad Sci USA 95(12) 6995-6999 Lohse MJ (1993) Molecular mechanisms of membrane receptor desensitization. Biochim Biophys Acta 1179(2) 171-188... [Pg.88]

Azzi, M., Charest, P. G., Angers, S., Rousseau, G., Kohout, T., Bouvier, M., and Pineyro, G. (2003). Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors. Proc. Natl. Acad. Sci. USA 100, 11406-11411. [Pg.160]

Chauvin, S., M. Bencsik,T. Bambino, and R.A. Nissenson. 2002. Parathyroid hormone receptor recycling role of receptor dephosphorylation and beta-arrestin. Mol. Endocrinol. 16 2720-2732. [Pg.324]

Pippig S., Andexinger S., Daniel K., Puzicha M., Caron M. G., Lefkowitz R. J. and Lohse M. J. (1993) Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors. J. Biol. Chem. 268, 3201-3208. [Pg.389]

Whistler JL, von Zastrow M. Morphine-activated opioid receptors elude desensitization by beta-arrestin. Proc Natl Acad Sci USA 1998 95 9914-9919. [Pg.233]

Fessart, D., Simaan, M., and Laporte, S. A. 2005. c-Src regulates clathrin adapter protein 2 interaction with beta-arrestin and the angiotensin II type 1 receptor during clathrin-mediated internalization. Mol Endocrinol 19 491-503. [Pg.109]

Kim, J., Ahn, S., Ren, X. R., et al. 2005b. Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling. Proc Natl Acad SciUSA 102 1442-1447. [Pg.111]

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