Decoy chemokine receptor

Chemokine Receptor Heterodimerization with Decoy Chemokine Receptor... 

D Amico, G. et al. (2000) Uncoupling of inflammatory chemokine receptors by 1L-10 generation of functional decoys. Nature Immunology, 1, 387—391. 

Galliera E, Jala VR, Trent JO, et al. beta-Arrestin-dependent constitutive internalization of the human chemokine decoy receptor D6. J Biol Chem 2004 279(24) 25590-25597. 

Comerford I, Nibbs RJ. Post-translational control of chemokines a role for decoy receptors Immunol Lett 2005 96(2) 163-174. 

Locati M, Torre YM, Galliera E, et al. Silent chemoattractant receptors D6 as a decoy and scavenger receptor for inflammatory CC chemokines. Cytokine Growth Factor Rev 2005 16 679-686. 

Martinez dlT, Locati M, Buracchi C, et al. Increased inflammation in mice deficient for the chemokine decoy receptor D6. Eur J Immunol 2005 35 1342-1346. 

Liu, L., K. Fujiki, B. Dixon and R.S. Sundick. Cloning of a novel rainbow trout (Oncorhynchus mykiss) CC chemokine with a fractalkine-like stalk and a TNF decoy receptor using cDNA fragments containing AU-rich elements. Cytokine 17 71-81, 2002. 

As mentioned earlier, the biological activities of chemokines are mediated by distinct members of the rhodopsin-like seven-transmembrane domain, G-protein-coupled receptor superfamily [65], Other receptors exist that bind chemokines with high affinity and specificity [16]. However, these receptors are structurally incapable of transducing signals and are therefore designated as decoy receptors. 

Mantovani, A., M. Locati, A. Vecchi, S. Sozzani and P. Allavena (2001). Decoy receptors a strategy to regulate inflammatory cytokines and chemokines. Trends Immunol 22(6) 328-336. 

Alexander JM. Structural basis of chemokine sequestration by a herpesvirus decoy receptor. Cell... 

Mahabaleshwar, H., Tarbashevich, K., Nowak, M., Brand, M., Raz, E. (2012). P-arrestin control of late endosomal sorting facilitates decoy receptor function and chemokine gradient formation. Development, 139, 2897—2902. 

Savino, B., Borroni, E. M., Torres, N. M., Proost, P., Struyf, S., Mortier, A., etal. (2009). Recognition versus adaptive up-regulation and degradation of CC chemokines by the chemokine decoy receptor D6 are determined by their N-terminal sequence. TheJournal of Biological Chemistry, 284, 26207—26215. 

Arnold PL, Fremont DH. Structural determinants of chemokine binding by an ectromelia virus-encoded decoy receptor. J Virol 2006 80(15) 7439-7449. 

Aleiandcr-Brett JM, Fremont DH. Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor. J Exp Med 2007 204(13) 3157-3172. 

Martin AP, Canasto-Chibuque C, Shang L et al. The chemokine decoy receptor M3 blocks CC chemokine ligand 2 and CXC chemokine ligand 13 function in vivo. J Immunol 2006 177(10) 7296-7302. 

S Bonecchi, R. et al. (2004) Differential recognition and scavenging of native and truncated macrophage-derived chemokine (macrophage-derived chemokine/CC chemokine ligand 22) by the D6 decoy receptor. Journal of Immunology (Baltimore, Md 1950), 172, 4972-4976. 

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