G-protein-coupled receptors signaling

Rogers TJ, Peterson PK (2003) Opioid G protein-coupled receptors signals at the crossroads of inflammation. Trends Immunol 24 116-121... 

G-protein coupled receptors Signal activates a G-protein that activates downstream enzymes—makes second messenger (cAMP or Ca2+). 

Luttrell, L. M. and Lefkowitz, R. I. The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. /. Cell Sci. 115 455-465, 2002. 

Hur, E. M. and Kim, K. T. (2002) G protein-coupled receptor signalling and cross-talk achieving rapidity and specificity. Cell. Signal. 14, 397 105. 

Alderton, F.A., Darroch, P.I., Sambi, B., McKie, A., Pyne, N.J. and Pyne, S., 2001, G-protein-coupled receptor signaling to p42/p44 mitogen-activated protein kinase is attenuated by Upid phosphate phosphatases 1,1a and 2 in HEK 293 cells, J. Biol. Chem. 276 13452-13460. 

Hall, R. A., and Lefkowitz, R. J. (2002) Regulation of G protein-coupled receptor signaling by scaffold proteins. Circ. Res. 91, 672-680. 

Hawes BE, Luttrell LM, Exum ST, Lefkowitz RJ (1994) Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor. J Biol Chem 269(22) 15776-15785... 

Hakak, Y., Shrestha, D., Goegel, M. C., Behan, D. P., and Chalmers, D. T. (2003). Global analysis of G-protein-coupled receptor signaling in human tissues. FEBS Lett. 550, 1-3. 

Head, B. P., Patel, H. H., Roth, D. M., Lai, N. C., Niesman, I. R., Farquhar, M. G., and Insel, P. A. (2005). G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes. / Biol. Chem. 280, 31036-31044. 

Ostrom, R. S., and Insel, P. A. (2004). The evolving role of lipid rafts and caveolae in G protein-coupled receptor signaling Implications for molecular pharmacology. 

KINETIC ANALYSIS OF G PROTEIN-COUPLED RECEPTOR SIGNALING USING FLUORESCENCE RESONANCE ENERGY TRANSFER IN LIVING CELLS... 

Chemosensory G-Protein-Coupled Receptor Signaling in the Brain... 

Kreienkamp HJ. Organisation of G protein-coupled receptor signalling complexes by scaffolding proteins. Curr Opin Pharmacol 2002 2 581-586. 

Chang, M., Zhang, L., Tam, J. P., and Sanders-Bush, E. (2000) Dissecting G protein-coupled receptor signaling pathways with membrane-permeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells. J. Biol. Chem. 275, 7021-7029. 

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