Bacterial growth, relationship

Contois DE (1959), Kinetics of bacterial growth relationship between population density and specific growth rate of continuous cultures, J. Gen. Microbiol. 21 40-50. 

When microorganisms use an organic compound as a sole carbon source, their specific growth rate is a function of chemical concentration and can be described by the Monod kinetic equation. This equation includes a number of empirical constants that depend on the characteristics of the microbes, pH, temperature, and nutrients.54 Depending on the relationship between substrate concentration and rate of bacterial growth, the Monod equation can be reduced to forms in which the rate of degradation is zero order with substrate concentration and first order with cell concentration, or second order with concentration and cell concentration.144... 

Bacterial Growth and Histamine Formation. The quantitative relationship between histamine formation and the microbial flora in skipjack tuna at 38 C is shown in Figure 3. At intervals during incubation samples were removed from the second section and assayed for histamine content and bacterial numbers. After 24 h the anaerobic bacterial count was 3.5 x 10 per g, and the histamine content was 297 mg per 100 g. Anaerobic counts were used to measure the microbial population because over 92% of the bacteria found in decomposed skipjack tuna were obligate or facultative anaerobes (Table I). 

Figure 3. Relationship of bacterial growth, expressed as generation time (g) to pH and temperature of wine during M-L fermentation...

The slopes and intercepts of Equations 8 and 9 are quite close, indicating that the molecular probes inhibiting the two superficially different processes are probably operating in the same way at the molecular level. Inhibition of luminescence appears to be different from inhibition of bacterial growth (compare Equation 9 with Equations 27 and 29). In various published (13) and unpublished results linear relationships with slopes of about 0.7 for the inhibition of bacterial growth have been found. 

The relationship between siderophore production and bacterial growth rates has led to the belief that siderophore prodnction contribntes to bacterial viralence. Rednced viralence of mntants deficient in siderophore production have been reported for Yersinia pestis, the cansative agent of... 

Figure 8.1 The relationship between bacterial growth efficiency and the C N ratio of the dissolved organic matter (DOM) substrate (C Ns).The curved indicate zero flux for a given bacterial C N (C Nb).Taken from Kirchman (2000).

In the laboratory, the relationship between an antimicrobial drug and a pathogen is described by the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC). The MIC is the lowest drug concentration that inhibits bacterial growth. The MBC is the lowest drug concentration that kills 99.9% of the bacteria. 

The relationship between nutrients and the growth of populations of microorganism can be described in three ways. The simplest theory is the one developed for organic-carbon-limited bacterial growth by Monod (1942) and popularised for application to phytoplankton by Dugdale (1967). In this MONOD theory, the rate of uptake of dissolved nutrient (per unit biomass) depends on ambient concentration S ... 

Seydel (1966) has shown that there is an approximate linear relationship between Hammett <7-values for various benzeneamines (related to the sulfonamides) and the logarithm of the lowest concentration of a sulfa drug to show inhibition of bacterial growth. The more positive the Hammett ortho-halogenated amine, which proved to give a more active sulfonamide than could be expected from its Hammett [Pg.403]

Mcllwain (240) has used the structural relationship between iodinin and the antagonistic quinones as a model for preparing quinoxaline di-i -oxides related to compounds of anti-hemorrhagic activity. The di-iV-oxides were inhibitory to bacterial growth, the parent diazines were inactive. These inhibitors were less active than iodinin. 

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