Mass spectrometry atmospheric pressure chemical ionisation

Olah, T. V., McLoughlin, D. A., Gilbert, J. D., The simultaneous determination of mixtures of drug candidates by liquid chromatography/ atmospheric pressure chemical ionisation mass spectrometry as an in-vivo drug screening procedure, Rapid Commun. Mass Spec. 1997, 11, 17—23. 

Tablets of famotidine, an anti-ulcer compound, were subjected to stress conditions in pack. Figure 9.34 indicates the profile obtained from analysis of an extract from the stressed tablets by LC-atmospheric pressure chemical ionisation mass spectrometry (APCIMS). The structure of famotidine is shown in Figure 9.35.

Taylor, A.J., Linforth, R.S.T., Harvey, B.A., Blake, B. (2000) Atmospheric pressure chemical ionisation mass spectrometry for in vivo analysis of volatile flavour release. Food Chem. 71 327-338. 

TA Gehring, LG Rushing, MI Churchwell, DR Doerge, KM Mcerlane, HC Thompson. HPLC determination of sulfadiazine residues in coho salmon (Oncorhynchus Kisutch) with confirmation by liquid chromatography with atmospheric pressure chemical ionisation mass spectrometry. J Agr Food Chem 44 3164-3169,1996. 

P. Dugo, L. Mondello, E. Sebastiani, R. Ottana, G. Errante and G. Dugo, Identification of minor oxygen heterocyclic compounds of citrus essential oils by hquid chromatography-atmospheric pressure chemical ionisation mass spectrometry , J. Fiq. Chromatogr. 22 2991-3005(1999). 

B. Herbreteau, A. Salvador, M. Lafosse and M. Dreux, SFC with evaporative lightscattering detection and atmospheric-pressure chemical-ionisation mass spectrometry for methylated glucoses and cyclodextrins analysis, Analusis 27 706-712 (1999). 

R.M. Black and R.W. Read, Application of liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry and tandem mass spectrometry to the analysis and identification of degradation products of chemical warfare agents, J. Chromatogr. A, 759, 79-92 (1997). 

Figure 6. Reconstructed ion current LC/APCI/MS (positive ion) chromatogram of a mixture of 19 analytes (each 10 J.g/ml in water). l.MPA, 2. TDGO, 3. triethanolamine, 4. jV-methyldiethanolaminc, 5. EPA, 6. iV-ethyldietha-nolamine, 7. thiodiglycol sulfone, 8. 3-quinuclidinol, 9. EMPA, 10. TDG, 11. n-PrPA, 12. diisopropylaminoethanol, 13. EEPA, 14. r -PrMPA, 15. tert-BuPA, 16. w-BuPA, 17. cHexMPA, 18. Pin MPA, 19. benzilic acid. (Reprinted from Journal of Chromatography A, 759, R.M. Black and R.W. Read, Application of liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry, and tandem mass spectrometry, to the analysis and identification of degradation products of chemical warfare agents, pp. 79-92 (1997), with permission from Elsevier)...

E. Razzazi-Fazeli, B. Rabus, B. Cecon and J. Bohm, Simultaneous quantification of A-tricho-thecene mycotoxins in grains using liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry, 7. Chromatogr., A, 968, 129-142 (2002). 

Jensen, A. G. Ndjoko, K. Wolfender, J. L. Hostettmann, K. Camponovo, E Soldati, F. Liquid chromatography-atmospheric pressure chemical ionisation/mass spectrometry A rapid and selective method for the quantitative determination of ginkgolides and hilohalide in Ginkgo leaf extracts and phytopharmaceuticals. Phytochem. Anal., 2002, 13 31-38. 

Adamowicz, P., Kala, M. Screening for drug-facilitated sexual assault by means of liquid chromatography coupled to atmospheric pressure chemical ionisation-mass spectrometry (LC APCl MS). Probl. Forensic Sci. 76, 403 11 (2008)... 

Talbot H. M., Watson D. F., Murrell J. C., Carter J. F., and Farrimond P. (2001) Analysis of intact bacteriohopanepo-lyols from methanotrophic bacteria by reversed phase high performance liquid chromatography-atmospheric pressure chemical ionisation-mass spectrometry. J. Chromatogr. A 921, 175-185. 

Parcerisa, J., Casals, I., Boatella, J., Codony, R., and Rafecas, M. 2000. Analysis of Olive and Hazelnut Oil Mixtures by High-Performance Liquid Chromatography — Atmospheric Pressure Chemical Ionisation Mass Spectrometry of Triacyglycerols and Gas-Liquid Chromatography of Non-Saponifiable Compounds (Tocopherols and Sterols). J. Chromatogr. A. 881 149-158. 

Clinton, R. and Creaser, C.S. (2005) Real-time monitoring of a pharmaceutical process reaction using a membrane interface combined with atmospheric pressure chemical ionisation mass spectrometry. Anal Chim Acta, 539 (1-2), 133-140. 

Sams M, Strutt P, Barnes K, et al.. Determination of dimetridazole, ronidazole and their common metabolite in poultry muscle and eggs by high performance liquid chromatography with UV detection and confirmatory analysis by atmospheric pressure chemical ionisation mass spectrometry. Analyst 1998 123 2545 -2549. 

Thompson TS, Noot DK, Calvert J, Pernal SF, Determination of lincomycin and tylosin residues in honey using sohd-phase extraction and liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry, J. Chro-matogr. A 2003 1020(2) 241-250. 

Byrdwell, W. C. and Emken, E. A. (1995) Analysis of triglycerides using atmospheric pressure chemical ionisation mass spectrometry. Lipidsy 30, 173-5. 

Kusaka, T., Ishihara, S., Sakaida, M. et al. (1996) Composition analysis of normal plant triacylglycerols and hydroperoxidised rac-l-stearoyl-2-oleoyl-3-linoleoyl-sn-glycerols by liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry. J. Chromatogr. A, 730, 1-7. 

Laakso, P. and Voutilainen, P. (1996) Analysis of triacylglycerols by silver ion high-performance atmospheric pressure chemical ionisation mass spectrometry. Lipids, 31, 1311-22. 

Moyano, E. McCullagh, M. Galceran, M.T. Games, D.E. Supercritical fluid chromatography-atmospheric pressure chemical ionisation mass spectrometry for the analysis of hydroxy polycychc aromatic hydrocarbons. J. Chromatogr. A, 1997, 777,167-176. 

Figure 4.2 Membrane inlet msiss spectrometry (a) schematic diagram of the membrane interface for APCI/MS and (b) schematic diagram of the donor/acceptor flow across the microporous membrane [69], Reprinted from Analytica Chimica Acta, 539, Clinton, R., Creaser, C.S., Bryant, D., Real-time Monitoring of a Pharmaceutical Process Reaction Using a Membrane Interface Combined with Atmospheric Pressure Chemical Ionisation Mass Spectrometry, 133-140. Copyright (2005), with permission from Elsevier...

Clinton, R., Creaser, C.S., Bryant, D. (2005) Real-time Monitoring of a Pharmaceutical Process Reaction Using a Membrane Interface Combined with Atmospheric Pressure Chemical Ionisation Mass Spectrometry. Anal. Chim. Acta 539 133-140. 

Mottram, H.R., Evershed, R.P. (1996) Structure analysis of triacylglycerol positional isomers using atmospheric pressure chemical ionisation mass spectrometry. Tetrahedron Letters, 37,8593-8596. 

Gan HH, Soukoulis C, Fisk 1. Atmospheric pressure chemical ionisation mass spectrometry analysis linked with chemometrics for food classification—a case study geographical provenance and cultivar classification of monovarietal clarified apple juices. Food Chem. 2014 146 149-56. 

Lopez-Roldan, P., Lopez de Alda, M.J., and Barcelo, D., Simultaneous determination of selected endocrine disrupters (pesticides, phenols and phthalates) in water by in-field solid-phase extraction (SPE) using the prototype PROFEXS followed by online SPE (PROSPEKT) and analysis by liquid chromatography-atmospheric pressure chemical ionisation-mass spectrometry, Anal. Bioanal. Chem., 378, 599, 2004. 

Kalman A, Mujahid C, Mother P, Heudi O. DeterminaHon of a-tocopherol in infant foods by liquid chromatography combined with atmospheric pressure chemical ionisation mass spectrometry. Rapid Comm Mass Spec 2003 17 723—7. 

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