Atherosclerosis garlic

Protective factors for atherosclerosis are fish oils, antioxidants, physical activity and garlic. These are discussed below. 

Garlic 2 3 61.21 million (38), Atherosclerosis, colon Breast cancer prevention. 

Bordia A. Effect of garlic on platelet aggregation in vitro. Atherosclerosis 1978 30 355-360. 

Garlic has been shown to prevent atherosclerosis and cancer and to retard the aging process. Alliin from garlic can scavenge OH, and garlic powder has been shown to scavenge both OH and l,l-diphenyl-2-picrylhydrazyl radicals. 

Clinical trials report antiplatelet effects following garlic ingestion and mixed effects on fibrinolytic activity. These effects in combination with antioxidant effects and reductions in total cholesterol may be beneficial in patients with atherosclerosis. In preliminary trials involving atherosclerotic patients, significant reductions in plaque volume were observed for patients taking garlic versus placebo. 

Berthold, H.K. and Sudhop, T. 1998. Garlic preparations for prevention of atherosclerosis. Curr. Opin. Lipidol. 9, 565—569. 

Gardner, C.D., Chatteijee, L.M., and Carlson, J.J. 2001. The effect of a garlic preparation on plasma lipid levels in moderately hypercholesterolemic adults. Atherosclerosis 154, 213—220. 

Jain, R.C. 1975. Onion and garlic an experimental cholesterol atherosclerosis in rabbits. Artery 1, 115-125. 

Munday, J.S., Jamesm, K.A., Fray, L.M., Kirkwood, S.W., and Thompson, K.G. 1999. Daily supplementation with aged garlic extract, but not raw garlic, protects low density lipoprotein against in vitro oxidation. Atherosclerosis 143, 399-404. 

In 1997, garlic was the most widely used natural supplement in US households. Garlic was shown to be used more than twice as much as any other natural supplement (5). Garlic is promoted to lower cholesterol and blood pressure, delay the progression of atherosclerosis, prevent heart disease, improve circulation, prevent cancer, and is used topically for tinea infections (3,4). 

Dirsch V, Kiemer A, Wagner H, Vollmar A. Effect of allicin and ajoene, two compounds of garlic, on inducible nitric oxide synthase. Atherosclerosis 1998 139 333-339. 

The relevance of platelet aggregation in the pathogenesis of atherosclerosis is well documented (Koscielny et al., 1998). The ability of garlic and its metabolites to prevent blood coagulation and platelet aggregation has been well established in numerous in vitro and in vivo (animals and humans) studies (Lawson et al., 1992 Han et al., 1995). 

Simons, L.A., Balasubramaniam, S., von Konigsmark, M., Parfitt, A., Simons, J. and Peters, W. (1995) On the effect of garlic on plasma lipids and lipoproteins in mild hyper-cholesterolaemia. Atherosclerosis. 113 219-225. 

The therapeutic indications for garlic bulb are prophylaxis of atherosclerosis treatment of elevated blood lipid levels, insufficiently influenced by diet improvement of the circulation in peripheral arterial vascular disease and respiratory infections and catarrhal conditions. 

Alkyl cysteines are water soluble organosulfiir compounds in garlic and are formed from the hydrolysis of y-glutamylcysteines. These compounds were found to possess activities in cancer prevention, atherosclerosis and neurotrophic disorders. 

Orekhov AN, Grunwald J. Effects of garlic on atherosclerosis. Nutrition 1997 13 656-663. 

Campbell JH, Efendy JL, Smith NJ, Campbell GR. Molecular basis by which garlic suppresses atherosclerosis. J Nutr 2001 131(3s) 1006S-1009S. 

Garlic helps prevent atherosclerosis and helps reduce your cholesterol level. ... 

Budoff MJ, Ahmadi N, Gul KM et al. Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis A randomized clinical trial. PtvveMive edicit 2009 49 101-107. 

Atherosclerosis cardiovascular disease garlic hypercholesterolemia sulfur compounds... 

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