Applications in Regenerative Medicine

Wang, X., Schroder, H.C., Muller, W.E., 2014. Enzymatically synthesized inorganic polymers as morphogenetically active bone scaffolds application in regenerative medicine. Int. Rev. Cell Mol. Biol. 27. 

Guelcher S. Biodegradable pol3mrethanes synthesis and applications in regenerative medicine. Tissue Eng B 2008 14(1) 3-17. 

Low molecular weight hydrogelators form one-dimensional (ID) stacks and, subsequently, gel networks in water. The behavior of these molecules in organic solvents is well known, and the ability to tune these materials lies in the power of the chemistry to be scalable. Therefore, we consider these materials promising for application in regenerative medicine and give a few examples. 

Skardal A (2014) Extracellular matrix-like hydrogels for applications in regenerative medicine. In Connon CJ, Hamley IW (eds) Hydrogels in cell-based therapies. Royal Society of Chemistry, Cambridge, doi 10.1039/9781782622055-00191... 

Besides the naturally occurring cationic PS chitin and chitosan, a huge variety of semi-synthetic products is available, which are based on anchoring cationic groups onto the polysaccharide backbone. Examples include cationic starch and cationic cellulose derivatives, which are widely used for industrial purposes (cationic starch in paper ) and also in medical applications (cationic cellulose as additives, e.g. JR-400 and Quatrisoft LM-200 in hygienic products). However, applications in regenerative medicine are rather poorly developed for these materials and therefore a discussion is excluded at this point. 

Still, with all these caveats, dendrimers have attracted attention in areas ranging from basic science to applications for approximately 30 years. Yet, dendrimers represent a largely unexplored class of molecules for applications in regenerative medicine. What factors make dendrimers interesting scaffolds in this regard ... 

Singh, V.K., Kalsan, M., Kumar, N., Saini, A., Chandra, R. Induced pluripotent stem cells Applications in regenerative medicine, disease modeling, and drug discovery. Frontiers in Cell and Developmental Biology 3, 2 (2015)... 

The use of nanotechnology for producing electrospun scaffolds of polyesters is the new frontier of tissue engineering for application in regenerative medicine. 

M. Peran, M.A. Garcia, E. Lopez-Ruiz, M. Bustamante, G. Jimenez, R. Madeddu, J.A. Marchall, Functionalized nanostructures with application in regenerative medicine. International Journal of Molecular Sciences, 13, 3847-3886, 2012. 

Green, D.W., Ben-Nissan, B., 2010. Biomimetic applications in regenerative medicine scaffolds, transplantation modules, tissue homing device and stem cells. Chapter 21. In Tochilin, V., Amiji, M. (Eds.), Handbook of Materials for Nanomedicine. Pan Stanford Publishing Pte Ltd, Singapore, pp. 821-850. ISBN 978-981-4267-55-7. 

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