Antimutagenic properties

RUKMINI c, KALPAGAM P (1985) Antimutagenic property of the imsaponifiable portion rice bran oil. In Antimutagenesis and Anticarcinogenesis Mechanisms. Eds Shankel D M, Hartman P E, Kada T, Holaender A, New York Plenum Press. 576. 

Vayalil PK. 2002. Antioxidant and antimutagenic properties of aqueous extract of date fruit (Phoenix dactylifera L. Arecaceae). J Agric Food Chem 50(3) 610-617. 

It was found that E. faecium strain M-74 has an important immunostimulatory and antimutagenic properties presented both in vitro and also in vivo (Ebringer et al. 1995 Mikes et al. 1995 Eerencik et al. 1999 Belicova et al. 2004,2007). The effects of the E. faecium enriched with organic selenium was studied in methotrexate treatment in rats with adjuvant arthritis. The results indicate that E. faecium may increase the preventive effects of methotrexate in rat adjuvant arthritis by improving its anti-inflamatory and antiarthritic effects (Rovensky et al. 2002). 

Differences in the mutagenic and antimutagenic properties of the stereoisomers of tetrahydro-p-carbolines (PTCCs)... 

Like other flavonoids, anthocyanins are also expected to have antioxidant and antimutagenic properties in vivo, although only limited data are available. From the published data, it appears that anthocyanins can be effective in vivo as antioxidants when included in the diet at 1 or 2g/kg diet in animal experiments. These levels in the diet provide 20 to 40 mg per day, levels that are much higher on a body-weight basis than found in the typical diet of humans. " ... 

Salikhova, R.A., N. Dulatova, and G.G. Poroshenko. 1993. [Studies of Angelica archangelica L. antimutagen properties by the micronucleus test]. Byull. Eksper. Biol. I Med. 115(4) 371-372. 

Salikhova, R. A., and G.G. Poroshenko. 1995. Antimutagenic properties of Angelica archangelica L. Vestn. Ross. Akad. Med. Nauk. 1 58-61. 

Schimmer, O., and H. Mauthener. 1996. Polymethoxylated xan-thones from the herb of Centaurium erythraea with strong antimutagenic properties in Salmonella tuphimurium. Planta Med. 62(6) 561-564. 

El Hamss, R., M. Idaomar, A. Alonso-Moraga, and A. Munoz Serrano. 2003. Antimutagenic properties of bell and black peppers. Food Chem. Toxicol. 41(l) 41-47. 

Zhang, H., B.S. Jeong, and T.H. Ma. 1999. Antimutagenic property of an herbal medicine. Polygonum multiflorum Thunb., detected by the Tradescantia micronucleus assay. /. Environ. Pathol. Toxicol. Oncol. 18(2) 127-130. 

Schimmer, O. Eschelbach, H. Esculetin in Alchemilla speciosa identification and antimutagenic properties. Pharmazie 1997, 52, 476 78. 

Other properties of psychollatine include antimutagenic properties in Saccharo-myces cerevisiae [128] and antioxidant activity against a variety of ROS [125,128]. The alkaloid was also capable of improving survival of antioxidant defense-deficient strains of yeast upon oxidative stress [128]. 

Fragoso V, Nascimento NC, Moura DJ, Silva ACR, Richter MF, Saffi J, Fett-Neto AG (2008) Antioxidant and antimutagenic properties of the monoterpene indole alkaloid psychollatine and the erode foliar extract of Psychotria umbellata Veil. Toxicol In Vitro 22 559-566. doi 10.1016/j.tiv.2007.11.010... 

About 300 individual compounds with antimutagenic properties are known. The frequency of mutations can be reduced by some amino acids (arginine, histidine, methionine, cysteamine etc ), vitamins and provitamins (a-tocopherol, ascorbic acid, retinol, p-carotene, phylloquinone, folic acid), enzymes (peroxidase, NADPH oxidase, glutathione peroxidase, catalase), complex compounds of plant and animal origin, chemical substances with antioxidant properties (derivatives of gallic acid, ionol, oxypyridines, selenium salts and others). 

Reports on antimutagenic properties of various eukaryotes have been reviewed by G. Hocman (1988, 1989). 

Langsrud T, Sorhaug T and Vegarud GE (1995) Protein degradation and amino acid metabolism by propionibacteria. Lait 75 325-330 Lankaputhra WEV and Shah NP (1998) Antimutagenic properties of probiotic bacteria and of organic acids. Mutat Res 397 169-182... 

Calle LM, Sullivan PD 1982 Screening of antioxidants and other compounds for antimutagenic properties towards benzo(a)pyrene-induced mutagenicity in strain Ta98 of Salmonella typhimurium. Mutat Res 101 99-114... 

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