Antimicrobial peptides derivatives

TABLE 15.2 Potential bioactive antimicrobial peptides derived from various fish proteins... 

Frece, V. (2006) QSAR analysis of antimicrobial and haemolytic effects of cyclic cationic antimicrobial peptides derived from protegrin-1. Bioorgan. Medic. Chem. 14, 6065-6074. 

Cationic Antimicrobial Peptide Derived from Polyhydroxyalkanoates... 

FIGURE 1.6 Molecules and their 3D shapes (a) H2O (water), (b) CH4 (methane), (c) Sg (elementary sulfur), (d) An assembly of six water molecules, (e) A small antimicrobial peptide derived from Helicobacter pylori (lOTO.pdb), drawn without atomic details. The term pdb means that the drawing was generated from data deposited in the Protein Data Bank hence, pdb. 

Tachyplesin I, an antimicrobial peptide derived from horseshoe crab Interaction with lipopolysaccharide (LPS) of the outer membrane of Gram-negative bacteria 137... 

Hussain, R., Joannou, C.L., Siligardi, G., 2006. Identification and characterization of novel lipophilic antimicrobial peptides derived from naturally occurring proteins. Int. J. PepL Res. Ther. 12, 269-273. http //dx.doi.org/10.1007/sl0989-006-9033A. 

PARK lY, PARK CB, KIM MS, KIM SC, PARASESI (1998), An antimicrobial peptide derived from histone H2A in the catfish, Parasilurus asotus, FEBS Lett, 437,258-62. 

PATRZYKAT A, GALLANT jw, SEO J-K, PYTYCK J, DOUGLAS SE. Novel antimicrobial peptides derived from flatfish genes. Antimicrob Agents Chemother 2003 August l 47(8) 2464-70. 

The magaiitins are a class of hnear, cationic, faciaUy amphipathic and hehcal antibacterial peptides derived from frog skin [51]. The magaiitins exhibit highly selective and potent antimicrobial activity against a broad spectrum of organisms [52, 53]. As these peptides are faciaUy amphipathic, the magainins have a cationic heli-... 

Antimicrobial peptides, 13 252-274 animal-derived, IS 253-254 identification of, 13 253 immune system response and, 13-255-256... 

Schittek B Deficiency of dermcidin-derived antimicrobial peptides in sweat of patients with atopic dermatitis correlates with an impaired innate defense of human skin in vivo. J Immunol 2005 174 8003-8010. 

Figure 1 Cartoon representation of the human cathelicidin hCAPI 8. The amino acid residues that define each of the three hCAP18 domains have been added. The sequence of LL-37, the host defense peptide derived from hCAP18, is found in the inset. Structure-activity relationship studies have identified regions within the peptide that are necessary for both antimicrobial and immunomodulatory activities.

Food-derived anticarcinogens, conjugated dienoic derivatives of linoleic acid, 262-270 Food quality health concerns, 5-6 maintenance by natural and synthetic compounds, 56-76 molecular s proaches to study, 1-6 related to antimicrobial peptides, 303-318 Foodbome pathogens, ionizing radiation, 296-298 Free radical(s) beef flavor peptides, 89-91 oxidation generating system, 88-89,91/ protein composition, 88-89,91/... 

The introduction of retro-, retro-inverso-, and PMRI-peptides with free and blocked C-and N-termini has been successful in numerous biological systems such as neurotransmitters, inhibitors of proteases and protein kinases, sweeteners, antimicrobial peptides, hormones, adhesion molecules, antigenic epitopes, immuno-modulators, and immunological probes. Table 1 provides an exhaustive list of retro-, retro-inverso-, PMRI-, and end-group-modified re/ro-mvmo-pseudopeptides derived from bioactive peptides. 

Shi, J., Ross, C.R., Chengappa, M.M., Sylte, M.J., McVey, D.S., and Blecha, F. (1996) Antibacterial activity of a synthetic peptide (PR-26) derived from PR-39, a praline-arginine-rich neutrophil antimicrobial peptide. Antimicrob. Agents Chemother. 40, 115-121. 

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