Antiinfective effect

Dalla Gosta, T., Nolting, A., Rand, K., and Derendorf, H., Pharmacokinetic-pharmacodynamic modeling of the in vitro antiinfective effect of piperacillin-tazobactam combinations, Int.. Clin. Pharmacol. Ther., 35, 426-433,1997. 

Probiotics are live microorganisms recognized as good or friendly bacteria, which settle in the intestine medium and render healthful effects on the host. Thus, these live microorganisms can improve microbial balances in intestine and exert positive effects on the host. Various health benefits have been attributed to probiotics such as antimutagenic and anticarcinogenic properties, antiinfection properties, immune system stimulation, and serum cholesterol reduction. " Lactobacillus and bifidobacteria are the most commonly used probiotics and are extensively investigated for their beneficial importance. ... 

Contrary to other whey proteins, a Fe " ion is present in lactoferrin molecule [3]. Similarly to immunoglobulins, it has the antimicrobial character [46]. Whey is appropriate for extraction of lactoferrin and cation-exchange chromatography is proposed for its purihcation. Heat treatment at pH 4.0 does not denature the protein therefore, this pH is suitable for its pasteurization. Recently, some beneficial aspects of lactoferrin on human s health have been regarded. Its exceptional properties such as antiinfective, anticancer, antioxidant and antimicrobial activities enhance its utility in pharmaceutical and food industries. Remarkably, lower pH values (2-3) enhance its antibacterial activity. The results of clinical studies about positive effects of lactoferrin on human and animals health have been published [49]. 

Schnitzler P, Schuhmacher A, Astani A et al (2008) Melissa officinalis oil affects infectivity of enveloped herpesviruses. Phytomedicine 15 734-740 Schuhmacher A, ReichUng 1, Schnitzler P (2003) Virucidal effect of peppermint oil on the enveloped viruses herpes simplex virus type 1 and type 2 in vitro. Phytomedicine 10 504-510 Semple SI, Nobbs SF, Pyke SM et al (1999) Antiviral flavonoid from Pterocaulon sphacelatum, an Australian Aboriginal medicine. 1 Ethnopharmacol 68 283-288 Semple SI, Pyke SM, Reynolds GD et al (2001) In vitro antiviral activity of the emthraquinone chrysophanic add agmnst poliovirus. Antiviral Res 49 169-178 Serkedjieva 1 (1997) Antiinfective activity of a plant preparation from Geranium sanguineum L. Pharmazie 52 799-802... 

Gilbert J, Senyuva HZ (2008) Bioactive compounds in foods. Blackwell Publishing, Oxford Goncagul G, Ayaz E (2010) Antimicrobial effect of garlic (Allium sativum). Recent Pat Antiinfect Drug Discov 5 1-3... 

---