Anabolic steroids adverse effects

In 1959 Clinton and coworkers reported the first synthesis of some pyrazole fused androstane derivatives and described their biological activity (B-76MI40404). Stanazolol (695) or 17-methyl-2iT-5o -androst-2-eno[3,2-c]pyrazol-17/3-ol was 10 times as active as 17a -methyltestosterone in improving nitrogen retention in rats (B-80MI40406), and its myotrophic activity was only twice that of 17a-methyltestosterone. It is used as an anabolic steroid with no lasting adverse side effects. 

Anabolic-androgenic steroids (AAS), which are analogs of the male hormone testosterone, are used among athletes and bodybuilders. AAS alter the hormonal systems of males and females, and induce many adverse effects. In addition to the sex-related changes, violent behavior and psychological dependence can also occur. The use of AAS in professional sports as well as in high school sports has aroused considerable attention. 

The use of anabolic steroids by athletes has received worldwide attention. Many athletes and their coaches believe that anabolic steroids— in doses 10-200 times larger than the daily normal production—increase strength and aggressiveness, thereby improving competitive performance. Such effects have been unequivocally demonstrated only in women. Furthermore, the adverse effects of these drugs clearly make their use inadvisable. 

While some anabolic steroids are still available in the legitimate trade, others are manufactured and distributed illegally, and the contents and potency of these are unknown some adverse effects could be due to impurities or content variation. 

Although concerns regarding the risk of anabolic steroids usually relate primarily to their peripheral and organic adverse effects, the fact that serious hypothala-mic pituitary dysfunction can occur, and can be slow to recover, is often overlooked. 

Maravelias C, Dona A, Stefanidou M, Spiliopoulou C. Adverse effects of anabolic steroids in athletes. A constant threat. Toxicol Lett. 2005 158 167-175. 

Some biochemical natural products have caused cardiotoxicity. Synthetic estrogens and progestins have been linked to cardiovascular disorders in women taking them for contraceptive purposes. Various animal and insect venoms and plant alkaloids may have adverse cardiovascular effects. There is some evidence to suggest that anabolic steroids, commonly linked to scandals involving athletes who take them to enhance performance, have caused cardiovascular disorders. 

In athletes Use of anabolic steroids, (for example, nandrolone [nan DRO lone] or stanozolol [sta NO zo lol], by athletes can cause premature closing of the epiphysis of the long bones, which interrupts development. The high doses taken by these young athletes may result in hepatic abnormalities, increased aggression ( roid rage"), and psychotic episodes, as well as the other adverse effects described above. 

Proponents of steroids say that adverse effects are rare and that medical science has failed to document any serious consequences of use. They say that instead of condemning nonmcdical use of anabolic steroids, researchers should be trying to invent new compounds that are anabolic without being significantly androgenic. 

Anabolic steroid abuse has been associated with a wide range of adverse side effects. Health consequences associated with anabolic steroid abuse... 

SIDE EFFECTS The unwanted effects or adverse reactions from using drugs read anabolic steroids. 

The report goes on to provide an extraordinarily detailed account of the adverse physical, mental, and social ill effects of anabolic steroid misuse. Some of the harmful physical effects are commonly self-reported, for example acne, endocrine effects, and gynecomastia in men however, others are rarer and therefore the causal link to use of anabolic steroids is equivocal Most of the harmful effects of anabolic steroids are not life-threatening, although a few deaths have been attributed to liver damage associated with long term steroid use. 

Many, but not all, of the adverse effects are reversible on withdrawal of anabolic steroids. However, there are special concerns about the use of anabolic steroids by young people, as the use of these substances can lead to virilization and, more broadly. 

Very high anabolic, moderate androgenic properties This injectable steroid is one of the most effective, yet associated with least number of adverse side-effects, steroid known. Both moderate strength and high size gains are noted. Deca is also known, to boost the immune system, while also adding in the rehabilitation of joint or tendon injuries and inflammation, like Tendonist. 

Very high anabolic, low androgenic properties This injectable / oral steroid is known for is effectiveness in both bulking and cutting (depending on what it s stacked with) utilized for bulking when stacked Testosterone or Dianabol, cutting when stacked with Winstrol or Anavar. Also associated with least number of adverse side-effects. This product is oil based so shots can be taken once a week. 

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