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Amphotericin B liposomal AmBisome

Amphotericin B (Amphocin) Amphotericin B Cholesteryl (Amphotec) Amphotericin B Lipid Complex (Abelcet) Amphotericin B Liposomal (AmBisome) Anidulafungin (Eraxis)... [Pg.36]

Lipid-associated formulations of amphotericin B, liposomal amphotericin B (AmBisome) and amphotericin B lipid complex (Abelcet) have been approved for use in proven cases of candidiasis however, patients with invasive candidiasis have also been treated successfully with amphotericin B colloid dispersion (Amphotec or Amphocil). The lipid-associated formulations are less toxic but as effective as amphotericin B deoxycholate. [Pg.435]

Several newer forms of amphotericin B (Abelcet, AmBisome, Amphotec) have also been developed. These drugs are encapsulated in small lipid spheres (liposomes) and then injected slowly by intravenous infusion.26,57 The lipid-based preparations appear to deliver higher doses of amphotericin B to the site of... [Pg.547]

Liposomal amphotericin B (AmBisome) may be more appropriate for disseminated disease. [Pg.427]

Solid-organ transplantation Liver transplantation Micafungin 50 mg (1 mg/kg in patients under 50 kg) IV daily Patients with two or more key risk factor Amphotericin B IV 10-20 mg daily or Liposomal amphotericin B (AmBisome) 1 mg/kg/day or flucona-... [Pg.436]

Liposomal amphotericin B (AmBisome) - Administer 3 mg/kg/day on days 1 through 5, 14 and 21 to immunocompetent patients a repeat course of therapy may be useful if parasitic clearance is not achieved. Administer 4 mg/kg/day on days 1 through 5, 10, 17, 24, 31, and 38 to immunosuppressed patients seek expert advice regarding further therapy if parasitic clearance is not achieved. [Pg.1666]

Berman JD. Editorial response U. S. Food and Drug Administration approval of AmBisome (Liposomal Amphotericin B) for treatment of visceral leishmaniasis. Clin Infect Dis 1999 28 49-51. [Pg.619]

Ambisome , Daunoxome , liposomal amphotericin B and daunorubicin citrate injection. Liposomal lurtotecan in phase I clinical trials. Gilead Sciences Inc., Foster City, CA. [Pg.371]

S. D. Allen, K. N. Sorensen, M. J. Nejdi, C. Durrant, and R. T. Proffit, Prophylactic efficacy of aerosolized liposomal (AmBisome) and non-liposomal (Fungizone) amphotericin B in murine pulmonary aspergillosis,./. Antimicrob. Chemother. 34 1001... [Pg.88]

A commercial product based on conventional liposomes has been introduced for the parenteral delivery of the anti-fungal drug, amphotericin B, which is poorly tolerated in conventional formulations. AmBisome, a liposomal formulation of amphotericin B, comprises SUV of diameter 50-100 ran. Two other lipid-based formulations of amphotericin B have also recently been commercially introduced ... [Pg.121]

Daunorabicin (DaunoXome, Gilead Sciences, Inc.) Doxorubicin (Doxil/Caelyx, Ortho Biotech ProductsLP/Sequus Pharmaceuticals) Amphotericin B (Ambisome/Abelcet, Fujisawa Healthcare, Wyeth Pharmaceuticals) Doxorubicin (Myocet/Evacet, Sopherion/ Liposome Company) Hepatitis A virus envelope proteins (Epaxal, Berna Biotech) Influenza virus (Inflexal V, Berna Biotech) Verteporfin (Visudyne, Novartis Ophthalmics) Kaposi s sarcoma Kaposi s sarcoma Fungal infections in immunocompromised patients Metastatic breast cancer Hepatitis A Influenza Age-related macular degeneration... [Pg.483]

Amphotericin B Abelcet (ABLC) [injectable 5 mg/ml, Upid complex],Ambisome (L-AMB) [injectable 50 mg/vial,liposomal].Amphocin (injectable 50 mg/vial, nonlipid),Amphotec (ABCD) [injectable 50 mg/vial, 100 mg/vial, colloidal dispersion], Fungizone [injectable 50 mg/vial, nonlipid], generic also available. [Pg.209]

Vineland, NJ) or over-the-counter cosmetic creams promoted for improved hydration (L Oreal, Paris and Dior, Paris). More recently, parenteral liposome formulations of amphotericin B, doxorubicin, and dau-norubicin have been approved and marketed (ABELCET, Elan, the Liposome Co., Inc, Princeton, NJ AmBisome and DaunoXome, Nexstar/Fujisawa, Deerfield Park, IL Amphotec and Doxil, Sequus/ Alza, Menlo Park, CA), with others on the horizon for applications in photodynamic therapy. Although the vast majority of liposome preparations are constructed from phospholipids, other nonphospholipid materials can be used either alone or in mixtures to form bilayer arrays. One such example is Amphotec, which utilizes sodium cholesteryl sulfate as the primary lipid. Other liposome forming materials may include but are not limited to fatty-acid compositions, ionized fatty acids, or fatty acyl amino acids, longchain fatty alcohols plus surfactants, ionized lysophospholipids or combinations, non-ionic or ionic surfactants and amphiphiles, alkyl maltosides, a-tocopherol esters, cholesterol esters, polyoxyethylene alkyl ethers, sorbitan alkyl esters, and polymerized phospholipid compositions. ° ... [Pg.984]

Berman JD, Badaro R, Thakur CP, Wasunna KM, Behbehani K, Davidson R, Kuzoe F, Pang L, Weerasuriya K, Bryceson AD. Efficacy and safety of liposomal amphotericin B (AmBisome) for visceral leishmaniasis in endemic developing countries. Bull World Health Organ 1998 76(l) 25-32. [Pg.207]

Walsh TJ, Goodman JL, Pappas P, Bekersky I, Buell DN, Roden M, Barrett J, Anaissie EJ. Safety, tolerance, and pharmacokinetics of high-dose liposomal amphotericin B (AmBisome) in patients infected with Aspergillus species and other filamentous fungi maximum tolerated dose study. Antimicrob Agents Chemother 2001 45(12) 3487-96. [Pg.207]

Weitkamp JH, Poets CF, Sievers R, Musswessels E, Groneck P, Thomas P, Bartmann P. Candida infection in very low birth-weight infants outcome and nephrotoxicity of treatment with liposomal amphotericin B (AmBisome). Infection 1998 26(1) II-I5. [Pg.210]

Proffitt RT, Satorius A, Chiang SM, et ai. Pharmacology and toxicology of a liposomal formulation of amphotericin B (AmBisome) in rodents. J Antimicrob Chemother 1991 28 SuppI B 49-61. [Pg.349]

Blau IW, Eauser AA. Review of comparative studies between conventional and liposomal amphotericin B(Ambisome) in neutropenic patients with fever of unknown origin and patients with systemic mycosis. Mycoses 2000 43 325-32. [Pg.350]

Annamycin PEG-liposomes Amphotericin B (AmBisome) Cytarabine (DepoCyt)... [Pg.4]

Ruijgrok EJ, Vulto AG, Van Etten EW. Aerosol delivery of amphotericin B Desoxycholate (Fungizone) and liposomal amphotericin B (AmBisome) aerosol characteristics and in-vivo amphotericin B deposiiton in rats. J Pharm Pharmacol 52(6) 619-627, 2000. [Pg.580]

See other pages where Amphotericin B liposomal AmBisome is mentioned: [Pg.75]    [Pg.75]    [Pg.75]    [Pg.75]    [Pg.335]    [Pg.1217]    [Pg.1462]    [Pg.1473]    [Pg.436]    [Pg.1669]    [Pg.598]    [Pg.405]    [Pg.406]    [Pg.316]    [Pg.316]    [Pg.423]    [Pg.265]    [Pg.3362]    [Pg.192]    [Pg.203]    [Pg.209]    [Pg.3]   
See also in sourсe #XX -- [ Pg.75 ]

See also in sourсe #XX -- [ Pg.75 ]

See also in sourсe #XX -- [ Pg.75 ]



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AmBisome

Ambisome (amphotericin

Amphotericin

Amphotericin B

Amphotericin B liposomal

Amphotericin, liposomal

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