Amphetamine sulphate

Lader, M., Comparison of amphetamine sulphate and caffeine citrate in man. Psychopharmacologia 14, 83-94, 1969. 

Example (+) Amphetamine Sulphate-a pri-amine salt, -Ephedrine Sulphate-a sec-amine salt, and Quinine Hydrochloride-a tert-amine salt. 

Illicit manufacture of amphetamine and methamphetamine scheduled substances and the approximate quantities of them required for the illicit manufacture of 100 kilograms of amphetamine sulphate and methamphetamine hydrochloride... 

Determination of the stability, in a formulation, of a drug with a propyl ester group. Determination of an amphetamine sulphate in tablet form. 

Drug takers using the service have typically been in their twenties and early thirties (with a mean age of 28). During the first twelve months of operation 57 per cent of clients had problems with opiates (mainly heroin) and 22 per cent with stimulants (mainly amphetamine sulphate). A large number (57 per cent) took their drugs by injection. Half of the team s contacts took place in clients homes, half in their own premises. Some in-patient contacts are made in the local psychiatric hospital, some in the regional detoxification unit at... 

Earlier attempts to effect an asymmetric coupling to mimic biological coupling reactions by using chiral copper(n)-amine complexes gave only low enantiomeric excesses.5 The use of (S)-( + )-amphetamine sulphate... 

L. Stomberg, Comparative gas chromatographic analysis of narcotics. Amphetamine sulphate, J. Chromatogr., 706 335 (1975). 

Amotril, All Amotriphene, xvii Amoxapine, 348 (metabolite), 713 Amoxican, 348 Amoxicillin(e), 348 Amoxil, 348 Amoxycillin, 348 Amoxycillin sodium, 348 Amoxycillin trihydrate, 348 Amoxypen, 348 Amperil, 351 Amphetamine, 349 (metabolite), 386, 764, 969 (-)-Amphetamine, 701 Amphetamine phosphate, 349 Amphetamine sulphate, 349 Amphetamines, gas chromatography, 17, 193 high pressure liquid chromatography, 214 metabolism, 287 thin-layer chromatography, 169 Amphicol, 443 Ampho-Moronal, 350 Amphotericin, 350 Ampicillin, 351... 

Berntman, L., Carlsson, C., Hagerdal, M., and Siesj6, B. K., 1977, Circulatory and metabolic effects in the brain induced by amphetamine sulphate, Acta Physiol. Scand. 102 310-323. 

FIG. 2. Structures of the investigated organic sulphate salts (X) chinine sulphate, (XI) strychnine sulphate, (XII) atropine sulphate, (XIII) bamethane sulphate, (XIV) isoprenaline sulphate, (XV) orciprenaline sulphate, (XVI) amphetamine sulphate. (Ref. 23)). 

Amphetamine sulphate and dexamphetamine sulphate, (C9Hi3N)2, H2SO4, Mol. Wt. 368 5. These are best determined by the following distillation method which is official in the B.P. 

Tablets of Amphetamine Sulphate B.P. Usually contain 5 mg of amphetamine sulphate.

Another method for rapid routine determination employs a spectro-photometric finish when the absorption characteristics of the amphetamine sulphate used are known. 

Transfer an amount of the powdered tablets equivalent to 25 mg of amphetamine sulphate to a separator containing 30 ml of water and 5 ml of O IN sodium hydroxide and shake to dissolve. Extract with four 30-ml portions of anaesthetic ether and wash the combined ether extracts with 2 ml of water. Run the ether solution into a wide-mouthed flask containing 20 ml of O IN sulphuric acid and evaporate the ether on a water-bath. Cool, transfer to a 50-ml graduated flask and make up to volume with 0-1N sulphuric acid. Centrifuge a portion of the solution and measure the maximum extinction of a 1 -cm layer of the clear supernatant liquid at about 257 mfJi using O IN sulphuric acid as reference and calculate the percentage of amphetamine sulphate in the original sample. 

Tablets of Methylamphetamine Hydrochloride, B,P, Usually contain 5 mg of methylamphetamine hydrochloride. The official assay is the distillation method given for amphetamine sulphate.

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