Ephedrine sulphate

Example (+) Amphetamine Sulphate-a pri-amine salt, -Ephedrine Sulphate-a sec-amine salt, and Quinine Hydrochloride-a tert-amine salt. 

CioHi50N,HC1, Mol. Wt. 201 7 ephedrine x 1 297 = ephedrine sulphate, (CioHi50N)2,H2S04, Mol. Wt. 428 6. Bromocresol green (Peterson ) and bromothymol blue (Moraw ) have also been recommended as suitable indicators. 

With potassium ferricyanide and sodium hydroxide solution ephedrine forms benzaldehyde. A solution of the hydrochloride gives with copper sulphate and sodium hydroxide solutions, a purple coloration extractable by ether, leaving the aqueous layer blue. A solution of ephedrine base in chloroform on standing is partially converted into ephedrine hydrochloride. ... 

Diethylcarbamazine Phenothiazine Octamylamine Amantadine Sulphate T etrahydrozoline Methylchlorophenoxyacetic Acid Carbaryl Thiabendazole Edrophonium Chloride Ephedrine Hydrochloride Methoxyamphetamine Hydrochloride... 

Ascorbic acid (+)-calcium pantothenate (-)-carvone anhydrous dextrose ephedrine hydrochloride (+)-litnonene L-lysine mannitol monosodium glutamate norephedrine hydrochloride quinidine sulphate quinine sulphate sorbitol L-threonine L-tryptophan tartaric acid all amino acids most sugars, e.g., glucose, xylose, ribose. 

The experimental results show that a simultaneous resemblance of ephedrine and Ca on the one side and of acetylcholine and K on the other side is present neither in sulphate colloids (agar) nor its substitute (Si02), nor in carboxyl colloids (pectinate) nor in the phosphate colloid nucleate but only in phosphatides. 

Efdiedrine, CnHjsON, crystallises from ether in rhombs, m.p. 118-9 , Md + 51 2 (EtOH), and, unlike ephedrine, is sparingly soluble in water. The hydrochloride, B. HCl, crystallises in colourless, slender needles, m.p. 181-2 , [a] -f- 62-05 (HjO), and, unlike the ephesulphate forms prisms, [a]i> + 52-5 the oxalate, m.p. 218 (dee.), unlike that of ephedrine, is readily soluble in water the aurichloride has m.p. 126-5-127-5 . Nitroso-0-ephedrine has m.p. 86 , and dibenzoyl- -ephedrine melts at 119-120 . By Mitchell s process d- -ephedrine yields an acetyl derivative, m.p. 103-5-104 ,... 

To an aqueous acid solution containing approximately 0-1 g of alkaloid, the volume of solution being kept low, add excess of solution of ammonia and extract with liberal portions of ether. As the alkaloid is very soluble in water, do not wash the ether extracts but dry them with anhydrous sodium sulphate before evaporating carefully. Dry the alkaloid in a desiccator. As a check after weighing the alkaloid, titrate as usual, using methyl red as indicator. 1 ml 0-lN = 0 01652 g of ephedrine ephedrine x 1 221 = ephedrine hydrochloride,... 

In ordcT to determine ephedrine in injections, dilute with water so that each ml may be expected to contain between 4 and 8 mg of base and appb the colour test described abo e to 1 ml of the dilution, com-nunemg with the addition of 01 ml of copper sulphate solution. 

Ephedrine is available as the anhydrous free base, the hemihydrate ( Vi H2O), hydrochloride or sulphate salts and appears as white crystalline powder or crystals. It is soluble in water and ethanol and exposure to light and air should be avoided. 

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