Amoxicillin NSAIDs

Unlabeled Uses H. pytori-associated duodenal ulcer (wifh amoxicillin and clarilhro-mycin), prevenfion and treatment of NSAID-induced ulcers, frealmenf of acfive benign gastric ulcers... 

Treatment of H. py/ori-associated duodenal ulcer (with amoxicillin, clarithromycin), active benign gastric ulcers. Prevention/ treatment of NSAID-induced ulcers. 

Clinically important, potentially hazardous interactions with acitretin, aldesleukin, aminoglycosides, amiodarone, amoxicillin, ampicillin, aspirin, bacampicillin, bismuth, carbenicillin, chloroquine, cisplatin, cloxacillin, co-trimoxazole, dapsone, demeclocycline, dexamethasone, diclofenac, dicloxacillin, etodolac, etoricoxib, etretinate, fenoprofen, flurbiprofen, folic acid antagonists, haloperidol, hydrocortisone, ibuprofen, indomethacin, influenza vaccines, ketoprofen, ketorolac, lithium, magnesium trisalicylate, meclofenamate, mefenamic acid, methicillin, mezlocillin, minocycline, nabumetone, nafcillin, naproxen, NSAIDs, omeprazole, oxacillin, oxaprozin, oxytetracycline, paromomycin, penicillin G, penicillin V, penicillins, phenylbutazone, piperacillin, piroxicam, polypeptide antibiotics, prednisolone, prednisone, probenecid, procarbazine, rofecoxib, salicylates, salsalate, sapropterin, sulfadiazine, sulfamethoxazole, sulfapyridine, sulfasalazine, sulfisoxazole, sulindac, tazobactum, tenoxicam, tetracycline, ticarcillin, tolmetin, trimethoprim, vaccines... 

Drugs that are the most common cause of TEN are allopurinol, ampicillin, amoxicillin, carbamazepine, NSAIDs, phenobarbital, pentamidine, phenytoin (diphenylhydantoin), pyrazolones, and sulfonamides. 

The treatment of PUD centers on the eradication of HP in HP-positive patients and reducing the risk of NSAID-induced ulcers and ulcer-related complications. Drug regimens containing antimicrobials such as clarithromycin, metronidazole, amoxicillin, and bismuth salts and antisecretory drugs such as the PPIs or H2RAS are used to relieve... 

Antibiotics Chronic infection with Helicobacter pylori is present in the great majority of patients with recurrent non-NSAID-induced peptic ulcers, and eradication of this organism greatly reduces the rate of recurrence of ulcer in these patients. The regimens of choice consist of a proton pump inhibitor plus a course of bismuth (Pepto-Bismol), tetracycline, and metronidazole or a course of amoxicillin plus clarithromycin. 

Hypersensitivity vasculitis induced by drags is another manifestation of a type III response. Drags involved include some p-lactams, particularly, amoxicillin and cephalexin, cotrimoxazole, NSAIDs, monoclonal antibodies, and chemotherapeutic drags such as tamoxifen and erlotinib. A proportion of small-vessel vasculitis patients have anti-neutrophil cytoplasmic antibodies. Although there is evidence of a pathogenic role for these antibodies and they are used as a diagnostic marker, operative mechanisms underlying this hypersensitivity state are still far from established. 

Pseudoallergic reactions resemble allergic reactions clinically but are not immunologically mediated. Examples include asthma and rashes caused by aspirin and maculopapular erythematous rashes due to ampicillin or amoxicillin in the absence of penicillin hypersensitivity. Few other entities that can initiate this reaction are sulfonamides, anticonvulsants (phenytoin, carbamazepine and phenobarbital), NSAIDs (aspirin, naproxen, nabumetone and keto-profen), antiretroviral agents and cephalosporins [1 ]. 

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